Results 61 to 70 of about 5,347,103 (256)
Not p-Values, Said a Little Bit Differently
As a contribution toward the ongoing discussion about the use and mis-use of p-values, numerical examples are presented demonstrating that a p-value can, as a practical matter, give you a really different answer than the one that you want.
Richard Startz
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
p value and confidence intervals
In any research after obtaining the results, the researcher wants to know whether the results obtained are statistically significant or not. The statistical significance is usually expressed as p value or confidence intervals.
Vivek Choudhury +2 more
doaj
Purpose Increasing attention has been directed towards the fragility index (FI) and reverse fragility index (RFI) in orthopaedic surgery. The purpose of this study was to amalgamate the FI and RFI literature in orthopaedic surgery, and critically ...
Hassaan Abdel Khalik +4 more
doaj +1 more source
P -value has been criticized because it is widely misunderstood and don′t tell the researchers what they want to know. Many clinical researches mistaken the conclusion of a significant P-value and may be exaggerate small and unimportant difference.
Areej Abdul Ghani Al Fattani
doaj +1 more source
P-values, p-values everywhere! [PDF]
Siva, Ganesh, Vanessa, Cave
openaire +2 more sources
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Current status of medical researchers’ understanding of P value
ObjectiveTo explore the understanding degree of medical students, researchers, and medical statistics teachers on P value in statistics and its related factors, so as to provide references for the improvement of medical statistics teaching ...
GUO Yibin, GUO Wei, WU Cheng
doaj +1 more source

