Results 91 to 100 of about 48,654 (175)

Sequence Inversion Dictates the Antiproliferative Activity of Bidirectional Tryptophan‐Containing Dipeptide Libraries

Journal of Peptide Science, Volume 32, Issue 10, October 2026.
Reversing the peptide backbone sequence of novel tryptophyl‐dipeptides uncovers profound changes in synthetic accessibility and antineoplastic profiles against human solid tumors. Phenotypic screening identifies a conformationally restricted lead architecture that achieves sub‐micromolar growth inhibition, confirming sequence topology as a critical ...
J. Benamer Díaz, Adam N. Khan, Aday González‐Bakker, José M. Padrón   +3 more
wiley   +1 more source

Phytochemicals as Multitarget Therapeutics in Pancreatic Cancer: Mechanisms, Clinical Evidence, and Translational Challenges

Phytotherapy Research, Volume 40, Issue 10, Page 5973-5987, October 2026.
Pancreatic cancer, particularly pancreatic ductal adenocarcinoma, is aggressive and often diagnosed late, making treatment challenging. This review highlights the potential of phytochemicals, such as curcumin and quercetin, as multitarget agents that influence key carcinogenic pathways. These compounds exhibit anticancer effects by inhibiting processes
Md. Rezaul Islam, Abdur Rauf, F. M. Shourav, Hanan A. Ogaly, Abdullah S. M. Aljohani, Waleed Al Abdulmonem, Kamala Badalova, Marcello Iriti   +7 more
wiley   +1 more source

Réunion du 1er‐2 mars et conclusions 

, 2012
Les 1er et 2 mars 2012, le Comité directeur (CD) intérimaire du Partenariat pour lutter contre l'aflatoxine en Afrique s'est réuni pour la première fois à Maputo (Mozambique). Ses représentants (liste des membres jointe, comme recommandé par l'UA BIRA,
PACA
core   +1 more source

PACA Strategy Development - Stakeholder consultation Workshop - 10-12 April 2013 [PDF]

, 2013
This is a workshop document on the PACA strategy development process - a stakeholder consultation workshop 10-12 April ...
PACA, Secretariat
core   +1 more source

Atributos de qualidade da carne de paca (Agouti paca): perfil sensorial e força de cisalhamento Quality attributes of paca meat (Agouti paca): sensory profile and shear force

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2013
Avaliaram-se as características sensoriais e determinou-se a força de cisalhamento de cortes de carne de paca (Agouti paca). As análises foram realizadas nos cortes desossados de paleta, lombo e pernil de nove pacas, preparados por cocção até a ...
C. Gomes, L.B. Karam, R.E.F. Macedo
doaj  

Communiqué : Réunion du Comité directeur du PACA – 25‐27 août 2013

, 2013
La deuxième réunion du Comité de direction (CD) du PACA de cette année civile sʹest tenue du 25 au 27 août 2013 à Johannesburg, en Afrique du Sud. Le sous‐comité Budget, finances et administration sʹest réuni le 25 août 2013 pour étudier et débattre du ...
PAC A
core   +1 more source

Modulation of Epithelial–Mesenchymal Transition Is a Possible Underlying Mechanism for Inducing Chemoresistance in MIA PaCa-2 Cells against Gemcitabine and Paclitaxel

Biomedicines
To elucidate the currently unknown molecular mechanisms responsible for the similarity and difference during the acquirement of resistance against gemcitabine (GEM) and paclitaxel (PTX) in patients with pancreatic carcinoma, we examined two-dimensional ...
Hajime Nakamura, Megumi Watanabe, Kohichi Takada, Tatsuya Sato, Fumihito Hikage, Araya Umetsu, Joji Muramatsu, Masato Furuhashi, Hiroshi Ohguro   +8 more
doaj   +1 more source

PACA Strategy Development – Stakeholder Consultation – Objectives and Strategic Thematic Areas for Action – April 2013 [PDF]

, 2013
This document presents the PACA Strategy Development process.
PACA, Secretariat
core   +1 more source

Grupo de Investigación PACA: Un proyecto en construcción

, 2009
El Grupo PACA (Programa de Acción Curricular Alternativo) nació en 1989; de él forman parte profesionales de varias universidades y funcionarios de entidades educativas. Fue creado formalmente como Grupo de Investigación de la Facultad de Educación de la
López Jiménez, Nelson Ernesto
core   +1 more source

Circulating Cell-Free Mitochondrial DNA and Inflammation in Older Adults with Pancreatic Cancer: Results from an Exploratory Study

Applied Sciences
Pancreatic cancer (PaCa) is among the most aggressive malignancies of the digestive system. Inflammation plays a critical role in tumor growth and dissemination, with soluble cytokines serving as messengers that facilitate interactions between immune and
Giulia Girolimetti, Flora Guerra, Leonardo Henry Umberto Eusebi, Claudio Ricci, Emanuele Marzetti, Anna Picca, Cecilia Bucci   +6 more
doaj   +1 more source