Results 71 to 80 of about 12,622 (179)

Gestational Diabetes Mellitus and Adverse Maternal and Neonatal Health Outcomes: an Umbrella review of Meta‐Analyses

open access: yesObesity Reviews, EarlyView.
ABSTRACT Introduction This study systematically synthesized evidence on adverse health outcomes related to gestational diabetes mellitus (GDM) via an umbrella review with integrated meta‐analyses. Methods The search covered publications from the database (PubMed/MEDLINE, Google Scholar, Embase, and CINAHL) inception to August 12, 2024. Meta‐analyses of
Jiseung Kang   +14 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, Volume 20, Issue 5, Page 1284-1298, May 2026.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Sexual and preventive behaviors associated with HAV, HBV, and HPV vaccine hesitancy among men who have sex with men in France

open access: yesHuman Vaccines & Immunotherapeutics
Vaccination coverage against hepatitis A virus (HAV), hepatitis B virus (HBV), and human papillomaviruses (HPV) is insufficient among men who have sex with men (MSM), partly because of their high prevalence of vaccine hesitancy (VH) specific to these ...
Chloé Cogordan   +15 more
doaj   +1 more source

Radiotherapy Enhancement by Gold Nanocluster‐functionalized Nanoliposomes Using Polychromatic Orthovoltage X‐ray Irradiation

open access: yesAdvanced Materials Interfaces, Volume 13, Issue 9, 5 May 2026.
Lipid drug carriers to which ultra‐small gold nanoparticles were added enabled more efficient radiotherapy of cultured pancreatic cancer tumors. These nanoparticles boosted radiation‐induced damage to tumors by generating more reactive molecules, though higher gold levels are needed for strong benefits.
Nazareth Milagros Carigga Gutierrez   +17 more
wiley   +1 more source

Water Deficit and Salinity Stress Reveal Many Specific QTL for Plant Growth and Fruit Quality Traits in Tomato

open access: yesFrontiers in Plant Science, 2018
Quality is a key trait in plant breeding, especially for fruit and vegetables. Quality involves several polygenic components, often influenced by environmental conditions with variable levels of genotype × environment interaction that must be considered ...
Isidore A. Diouf   +4 more
doaj   +1 more source

The Evolving Therapeutic Landscape of Gallic Acid: A Review of Mechanistic Insights and Clinical Potential

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 9, 13 May 2026.
ABSTRACT Gallic acid (GA), a plant‐derived phenolic compound, is evolving from a general antioxidant into a specific molecular modulator and a functional building block for advanced biomedical materials. This review synthesizes recent insights underpinned by GA's “redox duality”—its capacity to act as either a radical scavenger or a pro‐oxidant.
Woo Hyun Park
wiley   +1 more source

BIEN: A biodiversity informatics ecosystem advancing open and reproducible workflows for plant observation, plot and trait data

open access: yesMethods in Ecology and Evolution, Volume 17, Issue 5, Page 1556-1584, May 2026.
Abstract The rapid expansion of biodiversity data presents new opportunities to understand and forecast biosphere dynamics. However, disparate and dispersed data, taxonomic and geographic inconsistencies, pervasive quality issues, and a lack of reproducable workflows hinder synthesis, introduce biases and limit accurate assessment of biodiversity ...
Brian J. Enquist   +38 more
wiley   +1 more source

Long‐Term Stress Adaptation as a Highly‐Conserved Key Factor in Yeast Aging

open access: yesAging Cell, Volume 25, Issue 5, May 2026.
This study shows that long‐term, but not short‐term, stress exposure triggers molecular changes in yeast that mirror established hallmarks of aging, including altered proteostasis, epigenetic shifts, and reduced lifespan. These changes are reversible upon stress removal, and the genes involved are conserved across all domains of life. ABSTRACT Aging is
Yanzhuo Kong   +7 more
wiley   +1 more source

Agouti paca

open access: yes, 1993
Agouti paca (Linnaeus, 1766). Syst. Nat., 12th ed., 1:81. TYPE LOCALITY: French Guiana, Cayenne. DISTRIBUTION: SE San Luis Potosi (Mexico) to Paraguay, Guianas, and S Brazil. Introduced into Cuba. STATUS: CITES - Appendix III (Honduras). SYNONYMS: alba, fulvus, guanta, mexicanae, sublaevis, subniger, venezuelica.
openaire   +1 more source

Circ‐0030167/IGF2BP1 Induces Mitophagy‐Mediated Ferroptosis via HMOX1 mRNA Stabilization in Pancreatic Cancer

open access: yesCancer Science, Volume 117, Issue 5, Page 1362-1379, May 2026.
Our findings identify circ‐0030167/IGF2BP1/HMOX1 axis as a critical regulatory factor targeting mitochondria‐mediated ferroptosis, thereby presenting a novel therapeutic target for PC combination therapies. ABSTRACT Pancreatic cancer (PC) represents a highly aggressive malignancy characterized by a 5 year survival rate of less than 12%.
Qun Zhao   +6 more
wiley   +1 more source

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