The significance of exosomal RNAs in the development, diagnosis, and treatment of pancreatic cancer
Cancer Cell International, 2021 Exosomes are single-membrane, secreted organelles with a diameter of 30–200 nm, containing diverse bioactive constituents, including DNAs, RNAs, proteins, and lipids, with prominent molecular heterogeneity.
Zheng Zhao +5 more
doaj +1 more source
The Developing Left Superior Cervical Ganglion of Pacas (Agouti paca) [PDF]
The Anatomical Record, 2009 AbstractIn this study the main question investigated was the number and size of both binucleate and mononucleate superior cervical ganglion (SCG) neurons and, whether post‐natal development would affect these parameters. Twenty left SCGs from 20 male pacas were used.
Melo, SR +8 more
openaire +4 more sources
An Integrative Pancreatic Cancer Risk Prediction Model in the UK Biobank
Biomedicines, 2023 Pancreatic cancer (PaCa) is a lethal cancer with an increasing incidence, highlighting the need for early prevention strategies. There is a lack of a comprehensive PaCa predictive model derived from large prospective cohorts. Therefore, we have developed
Te-Min Ke +2 more
doaj +1 more source
Lipophilic statins inhibit YAP nuclear localization, co-activator activity and colony formation in pancreatic cancer cells and prevent the initial stages of pancreatic ductal adenocarcinoma in KrasG12D mice. [PDF]
, 2019 We examined the impact of statins on Yes-associated Protein (YAP) localization, phosphorylation and transcriptional activity in human and mouse pancreatic ductal adenocarcinoma (PDAC) cells.
Chang, Hui-Hua +7 more
core +2 more sources
Caecotrophy in pacas (Agouti paca Linnaeus, 1766)
, 2001 (Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
Sabatini, Vera +1 more
openaire +2 more sources
Optical/NIR stellar absorption and emission-line indices from luminous infrared galaxies [PDF]
, 2019 We analyze a set of optical-to-near-infrared long-slit nuclear spectra of 16 infrared-luminous spiral galaxies. All of the studied sources present H$_2$ emission, which reflects the star-forming nature of our sample, and they clearly display H I emission
Bonatto, Charles +13 more
core +3 more sources
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Miologia do membro pélvico da paca (Cuniculus paca Linnaeus, 1766)
Pesquisa Veterinária Brasileira, 2015 Resumo: Objetivam-se descrever os músculos do membro pélvico da paca (Cuniculus paca Linnaeus, 1766), mediante dissecção anatômica dessa região. Foram utilizadas dez Cuniculus paca adultas, machos e fêmeas, pesando entre cinco e 10 kg do plantel de pacas
Leonardo M. Leal +5 more
doaj +1 more source
Clinical significance and correlation of PD-L1, B7-H3, B7-H4, and TILs in pancreatic cancer
BMC Cancer, 2022 Background B7 molecules play significant roles in regulating tumor immunity, but their expression patterns and immuno-biological correlations in pancreatic cancer (PaCa) have not been fully discussed.
Jiayue Yang +8 more
doaj +1 more source