Results 21 to 30 of about 48,654 (175)
International Journal of Qualitative Studies on Health & Well-Being, 2020 Purpose: Vaccine hesitancy is common in France, including among general practitioners (GPs). We aimed to understand vaccine hesitant GPs’ views towards vaccines. Method: We conducted in-depth interviews that were thematically analysed.
Rose Jane Isobel Wilson +4 more
doaj +1 more source
Communiqué: PACA Steering Committee Addis Ababa, Ethiopia 30 October - 1 November 2012 Meeting and Outcomes [PDF]
, 2012 On 31 October 2012, the African Union Commission (AUC) hosted the launch ceremony for the Partnership for Aflatoxin Control in Africa (PACA), and inaugurated the PACA SC.
PACA
core +1 more source
A Conserved Isoleucine Gates the Diffusion of CO and O2 to the Active Site of NiFe CO‐Dehydrogenase
Angewandte Chemie, EarlyView.A combination of protein film electrochemistry and site‐directed mutagenesis shows that isoleucine 563 (numbering of Thermococcus sp. AM4) gates the arrival of both CO and O2 to the active site of the nickel‐iron CO dehydrogenases. Mutations at this position increase the resistance to O2 at the cost of a slower reaction with CO.
Laura Opdam +7 more
wiley +2 more sources
Angewandte Chemie, EarlyView.PQB‐4, a fluorescent small‐molecule ligand that targets c‐MYC DNA G‐quadruplexes (G4s), showed marked synergy with gemcitabine in resistant PANC‐1 cells (CI = 0.027). In vivo, the ligand reduced tumor weight by 44% in a PANC‐1 xenograft model. These results highlight the therapeutic potential of c‐MYC DNA G4‐targeting ligands for treating gemcitabine ...
Bo‐Xin Zheng +10 more
wiley +2 more sources
BMC Plant Biology, 2019 Background Diseases caused by Pseudomonas syringae (Ps) are recognized as the most damaging factors in fruit trees with a significant economic and sanitary impact on crops.
Mariem Omrani +5 more
doaj +1 more source
Life, 2023 Pancreatic cancer (PACA) is a highly malignant tumor with a poor prognosis. Recent studies have discovered substantial differences in the expression levels of several circadian genes in PACA samples compared to normal samples.
Qingqing Wang +7 more
doaj +1 more source
The significance of exosomal RNAs in the development, diagnosis, and treatment of pancreatic cancer
Cancer Cell International, 2021 Exosomes are single-membrane, secreted organelles with a diameter of 30–200 nm, containing diverse bioactive constituents, including DNAs, RNAs, proteins, and lipids, with prominent molecular heterogeneity.
Zheng Zhao +5 more
doaj +1 more source
Report of the Partnership for Aflatoxin Control in Africa (PACA) Workshop [PDF]
, 2011 This reports presents outcomes of a workshop that PACA convened as its first organizational planning meeting under the auspices of the AUC in Nairobi, Kenya on October 3-4, 2011 sponsored by USAID. Forty-one participants representing AUC member countries,
PACA
core +1 more source
An Integrative Pancreatic Cancer Risk Prediction Model in the UK Biobank
Biomedicines, 2023 Pancreatic cancer (PaCa) is a lethal cancer with an increasing incidence, highlighting the need for early prevention strategies. There is a lack of a comprehensive PaCa predictive model derived from large prospective cohorts. Therefore, we have developed
Te-Min Ke +2 more
doaj +1 more source
Advanced Science, EarlyView.A schematic model summarizing GNA15's mechanism in mediating macrophage M2 polarization and Gemcitabine resistance. ABSTRACT The complexity of pancreatic ductal adenocarcinoma (PDAC) progression, coupled with the lack of effective immunotherapy, underscores the imperative to deepen our understanding of its mechanisms and identify suitable immune ...
Weihui Guo +8 more
wiley +1 more source