Results 1 to 10 of about 48,654 (175)

Multi-Omics and Computational Pharmacology Approach With Experimental Validation Reveals the Antiproliferative Activity of Sophoricoside Against Pancreatic Cancer. [PDF]

Chem Biodivers
An integrated pipeline combining network pharmacology, machine learning, and multi‑omics reveals that sophoricoside suppresses pancreatic cancer cell proliferation through PTPN1, a downstream effector. Elevated PTPN1 correlates with poor prognosis and immune infiltration, positioning it as a promising therapeutic node and prognostic biomarker for this ...
Lin P, Cheng W, Qi X, Li J.
europepmc   +2 more sources

Propriedades tensiométricas do peritônio da paca (Cuniculus paca) a fresco e conservado em glicerina 98% [PDF]

Pesquisa Veterinária Brasileira, 2014
Na busca constante, tanto de material biológico alternativo para a realização de implantes, quanto de novas opções de modelos de experimentação animal, o objetivo desta investigação foi descrever o comportamento mecânico do peritônio da paca (Cuniculus ...
Angela Daniele de Camargo, Paulo César de Camargo, Leonardo Martins Leal, Sérgio Pinter Garcia Filho, Leandro Luís Martins, Antônio Carlos Shimano, Márcia Rita Fernandes Machado   +6 more
doaj   +3 more sources

Anatomic study of the arterial vascularization of the brain base of paca (Cuniculus paca) [PDF]

Pesquisa Veterinária Brasileira, 2020
: Paca (Cuniculus paca Linnaeus, 1766), rodent belong to the Cuniculidae family, has encouraged numerous scientific researches and for this reason could be an experimental model in both human and veterinary areas.
Tais H.C. Sasahara, Vitória F.N.P. Fontes, Débora O. Garcia, Daniel W. Rocha, Fabrício S. Oliveira, Leonardo M. Leal, Marcia Rita F. Machado, Fernanda G.G. Dias   +7 more
doaj   +1 more source

Qualitative and quantitative comparison of cell-free DNA and cell-free fetal DNA isolation by four (semi-)automated extraction methods: impact in two clinical applications: chimerism quantification and noninvasive prenatal diagnosis

Journal of Translational Medicine, 2021
Background Non-invasive molecular analysis of cell-free DNA (cfDNA) became a sensitive biomarker for monitoring organ transplantation or for detection of fetal DNA (cffDNA) in noninvasive prenatal test. In this study, we compared the efficiencies of four
Pascal Pedini, Hajer Graiet, Laurine Laget, Lugdivine Filosa, Jade Chatron, Nicem Cherouat, Jacques Chiaroni, Lucas Hubert, Coralie Frassati, Christophe Picard   +9 more
doaj   +1 more source

Motivational interview training improves self-efficacy of GP interns in vaccination consultations: A study using the Pro-VC-Be to measure vaccine confidence determinants

Human Vaccines & Immunotherapeutics, 2023
Immunization-specific motivational interviewing (MI), a patient-centered communication style used to encourage internal motivation for attitudinal and behavioral change, can provide healthcare professionals (HCPs) with the skills and practice required to
Amanda Garrison, Lisa Fressard, Eva Mitilian, Virginie Gosselin, Patrick Berthiaume, Ludovic Casanova, Arnaud Gagneur, Pierre Verger   +7 more
doaj   +1 more source

Gradient of vaccine hesitancy among French men having sex with men: An electronic cross-sectional survey in 2022

Human Vaccines & Immunotherapeutics, 2023
In developed countries, vaccinations against hepatitis B (HBV), hepatitis A (HAV), and human papillomavirus (HPV) are often recommended to men who have sex with men (MSM) because of the risky sexual practices in which some engage.
Emeline Brosset, Lisa Fressard, Chloé Cogordan, Aurélie Bocquier, Annie Velter, Margot Annequin, Michel Bourrelly, Jean Constance, David Michels, Marion Mora, Stéphane Morel, Camilla Oliveri, Gwenaëlle Maradan, Cyril Berenger, Bruno Spire, Pierre Verger   +15 more
doaj   +1 more source

Online study of health professionals about their vaccination attitudes and behavior in the COVID-19 era: addressing participation bias

Human Vaccines & Immunotherapeutics, 2021
Online surveys of health professionals have become increasingly popular during the COVID-19 crisis because of their ease, speed of implementation, and low cost. This article leverages an online survey of general practitioners’ (GPs’) attitudes toward the
Pierre Verger, Dimitri Scronias, Yves Fradier, Malika Meziani, Bruno Ventelou   +4 more
doaj   +1 more source

Study protocol for a pragmatic cluster randomized controlled trial to improve dietary diversity and physical fitness among older people who live at home (the “ALAPAGE study”)

BMC Geriatrics, 2022
Background Diet and physical activity are key components of healthy aging. Current interventions that promote healthy eating and physical activity among the elderly have limitations and evidence of French interventions’ effectiveness is lacking.
Aurélie Bocquier, Anne-Fleur Jacquemot, Christophe Dubois, Hélène Tréhard, Chloé Cogordan, Gwenaëlle Maradan, Sébastien Cortaredona, Lisa Fressard, Bérengère Davin-Casalena, Agnès Vinet, Pierre Verger, Nicole Darmon, on behalf of the ALAPAGE Study Group, Valérie Arquier, Guillaume Briclot, Rachel Chamla, Florence Cousson-Gélie, Sarah Danthony, Karin Delrieu, Julie Dessirier, Catherine Féart, Christine Fusinati, Rozenn Gazan, Mélissa Gibert, Valérie Lamiraud, Matthieu Maillot, Dolorès Nadal, Christelle Trotta, Eric O. Verger, Valérie Viriot   +29 more
doaj   +1 more source

Plant genetic background increasing the efficiency and durability of major resistance genes to root-knot nematodes can be resolved into a few resistance QTLs

Frontiers in Plant Science, 2016
With the banning of most chemical nematicides, the control of root-knot nematodes (RKNs) in vegetable crops is now based essentially on the deployment of single, major resistance genes (R-genes).
Arnaud eBarbary, Caroline eDjian_Caporalino, Philippe eCastagnone-Sereno, Nathalie eMarteu, Arianne eFazari, Bernard eCaromel, Alain ePalloix   +6 more
doaj   +1 more source

Changes in general practitioners’ attitudes toward COVID-19 vaccination after first interim results: a longitudinal approach in France

Human Vaccines & Immunotherapeutics, 2021
We assessed whether the a priori acceptance by French general practitioners (GPs) of COVID-19 vaccines changed after the announcements about them in November 2020.
Pierre Verger, Dimitri Scronias
doaj   +1 more source