Results 41 to 50 of about 42,730 (222)

An Integrative Pancreatic Cancer Risk Prediction Model in the UK Biobank

Biomedicines, 2023
Pancreatic cancer (PaCa) is a lethal cancer with an increasing incidence, highlighting the need for early prevention strategies. There is a lack of a comprehensive PaCa predictive model derived from large prospective cohorts. Therefore, we have developed
Te-Min Ke, Artitaya Lophatananon, Kenneth R. Muir   +2 more
doaj   +1 more source

Caecotrophy in pacas (Agouti paca Linnaeus, 1766)

, 2001
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
Sabatini, Vera, De Costa, M. J. R. Paranhos   +1 more
openaire   +3 more sources

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

Advanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi, Hangqi Liu, Jianru Sun, Xiaoding Liu, Xinping Jv, Longyun Chen, Yuhan Zhang, Hui Zhang, Xudong Xing, Ruiyu Li, Xinyi Ke, Jun Wang, Xianglin Yin, Bohan Liu, Qixian Liu, Yuan Wang, Junliang Lu, Shiyi Liu, Junyi Pang, Yumeng Cai, Menghua Dai, Fan Bai, Huanwen Wu, Zhiyong Liang   +23 more
wiley   +1 more source

Communiqué: PACA Steering Committee Addis Ababa, Ethiopia 30 October - 1 November 2012 Meeting and Outcomes [PDF]

, 2012
On 31 October 2012, the African Union Commission (AUC) hosted the launch ceremony for the Partnership for Aflatoxin Control in Africa (PACA), and inaugurated the PACA SC.
PACA
core  

The Host Cell Factor Phosphatase‐2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type‐1

Advanced Science, EarlyView.
Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth, Christoph F. Jacob, Alexandra Nguyen, Mandy Beyer, Andreas O. Mieland, Mario Dejung, Jia‐Xuan Chen, Walburgis Brenner, Christina Ehrhardt, Andreas Henke, Oliver H. Krämer   +10 more
wiley   +1 more source

MONITORING OF THE INTESTINAL TRACT PARASITE LOAD AND OF THE SANITARY MANGEMENT AT A PACA BREEDING FARM

Ciência Animal Brasileira, 2015
Paca (Cuniculus paca Linnaeus, 1766) rearing has shown development in all Latin America countries. Fresh feces samples were collected from the soil and analyzed by Willis Mollay and Hoffmann’s techniques, aiming at accompanying the sanitary management ...
Vânia Maria França Ribeiro, Soraia Figueiredo de Souza, Nayara Moreira Pinto de Mesquita, Augusto Luiz Faino Alves, Francisco Glauco de Araújo Santos   +4 more
doaj   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Eutrombicula pacae

, 2022
Eutrombicula pacae (Floch and Fauran, 1957) (Figs. 16–18) Trombicula (Eutrombicula) pacae Floch and Fauran, 1957: 1, fig. 1. Eutrombicula pacae: Brennan & Reed 1974: 710; Loomis & Wrenn 1984: 158; Stekolnikov et al. 2007: 65. Diagnosis. SIF = 7BS-N-2-3111.1000; fsp = 7.7.7; fCx = 1.1.1; fSt = 2.2; fPp = B/B(N)/NNN; fSc: PL ≥ AM> AL; Ip = 764–810; fD ...
Stekolnikov, Alexandr A., Capek, Miroslav, Literák, Ivan   +2 more
openaire   +2 more sources

Clinical significance and correlation of PD-L1, B7-H3, B7-H4, and TILs in pancreatic cancer

BMC Cancer, 2022
Background B7 molecules play significant roles in regulating tumor immunity, but their expression patterns and immuno-biological correlations in pancreatic cancer (PaCa) have not been fully discussed.
Jiayue Yang, Zhen Tian, Han Gao, Fan Xiong, Cuiping Cao, Jiaojiao Yu, Wei Shi, Qiang Zhan, Cheng Yang   +8 more
doaj   +1 more source

ABHD17C‐Mediated S‐Depalmitoylation of BCL6B Enhances CD24 Transcription to Resist Macrophage Phagocytosis in Pancreatic Cancer

Advanced Science, EarlyView.
ABHD17C‐mediated depalmitoylation of BCL6B at Cys442 blocks its nuclear import and triggers ubiquitin‐dependent degradation, attenuating transcriptional repression of the anti‐phagocytic signal CD24. This mechanism enables pancreatic cancer cells to evade macrophage phagocytosis and fosters an immunosuppressive microenvironment.
Yalu Zhang, Di Cui, Fanzheng Meng, Xu Zhu, Liang Zhu, Liang Wu, Haifeng Hu, Jizhou Wang, Hanhui Yao, Lianxin Liu   +9 more
wiley   +1 more source