Results 251 to 260 of about 41,121 (277)
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Inversion detection using PacBio long reads
2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), 2017Structural variation is important in disease etiology and ecological adaptation. Prior work has focused on using either only short paired-end reads or a hybrid approach that combines long and short reads to detect structural variants. Few methods have focused solely on using long reads.
Shenglong Zhu +2 more
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C&EN Global Enterprise, 2020
Faced with resistance from antitrust authorities concerned about reduced competition, Illumina has dropped plans to acquire its next-generation DNA-sequencing (NGS) rivalPacific Biosciences of Cali...
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Faced with resistance from antitrust authorities concerned about reduced competition, Illumina has dropped plans to acquire its next-generation DNA-sequencing (NGS) rivalPacific Biosciences of Cali...
openaire +1 more source
Improved Performance of the PacBio SMRT Technology for 16S rDNA Sequencing
Journal of Microbiological Methods, 2014Improved sequencing accuracy was obtained with 16S amplicons from environmental samples and a known pure culture when upgraded Pacific Biosciences (PacBio) hardware and enzymes were used for the single molecule, real-time (SMRT) sequencing platform.
Jinjun Kan +2 more
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Informatics for PacBio Long Reads
2019In this article, we review the development of a wide variety of bioinformatics software implementing state-of-the-art algorithms since the introduction of SMRT sequencing technology into the field. We focus on the three major categories of development: read mapping (aligning to reference genomes), de novo assembly, and detection of structural variants.
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Full-Length Mitochondrial-DNA Sequencing on the PacBio RSII
2016Conventional mitochondrial-DNA (MT DNA) sequencing approaches use Sanger sequencing of 20-40 partially overlapping PCR fragments per individual, which is a time- and resource-consuming process. We have developed a high-throughput, accurate, fast, and cost-effective human MT DNA sequencing approach.
Rolf H A M, Vossen, Henk P J, Buermans
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US FTC challenges Illumina’s purchase of PacBio
C&EN Global Enterprise, 2020The US Federal Trade Commission has challenged Illumina’s planned $1.2 billion acquisition of Pacific Biosciences of California, its smaller next-generation DNA-sequencing (NGS) rival. The antitrust regulator says it has ordered an administrative trial on the deal for August and will seek a restraining order in federal court if necessary to prevent it ...
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Sample and Library Preparation for PacBio Long-Read Sequencing in Grapevine
PacBio long-read sequencing is a third-generation technology that generates long reads up to 20 kilobases (kb), unlike short-read sequencing instruments that produce up to 600 bases. Long-read sequencing is particularly advantageous in higher organisms, such as humans and plants, where repetitive regions in the genome are more abundant. The PacBio long-Hymavathi, Salava +3 more
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Identification of alfalfa lncRNAs based on PacBio sequencing
Grass Research, 2023Yue Li +7 more
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