Results 121 to 130 of about 2,076,709 (312)

replication-package-mioeda-study.zip

open access: yes
Replication package for mioeda study. (Unzip with 7z on Windows if builtin zip utility doesn't work.)
Anonymous Anonymous (4854526)
core   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Fechnerian Scaling in R: The Package fechner [PDF]

open access: yes
Fechnerian scaling is a procedure for constructing a metric on a set of objects (e.g., colors, symbols, X-ray films, or even statistical models) to represent dissimilarities among the objects "from the point of view" of a system (e.g., person, technical ...
Ali Ünlü   +2 more
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Tools for Exploring Multivariate Data: The Package ICS [PDF]

open access: yes
Invariant coordinate selection (ICS) has recently been introduced as a method for exploring multivariate data. It includes as a special case a method for recovering the unmixing matrix in independent components analysis (ICA).
Klaus Nordhausen   +2 more
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Smart Packaging Main Trends [PDF]

open access: yesOvidius University Annals: Economic Sciences Series
Globalization, innovative technologies and the ever-increasing demands of consumers have a significant influence on the packaging industry, which is constantly growing.
Anca Cristina Stanciu
doaj  

Unified Geostatistical Modeling for Data Fusion and Spatial Heteroskedasticity with R Package ramps [PDF]

open access: yes
This article illustrates usage of the ramps R package, which implements the reparameterized and marginalized posterior sampling (RAMPS) algorithm for complex Bayesian geostatistical models.
Mary Kathryn Cowles   +2 more
core  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

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