Results 151 to 160 of about 14,587,402 (349)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Raising The Security levels of Government Documents by Digitally including QR codes with biometric information for Authorized Holders

open access: yesJournal of Architecture, Art & Humanistic Science
Digital printing, with its modern concept and capabilities, has brought about a real revolution in the security printing industry. Indeed, such systems have developed, and their security capabilities have increased. Rather, the matter has gone beyond the
Prof. Ahmed Mahmoud Yousry   +2 more
doaj   +1 more source

Die shift prediction of fan out panel level packages considering both warpage and flow induced mechanisms with temperature dependent properties

open access: yesScientific Reports
Fan-out panel-level packaging is a leading technology in advanced semiconductor manufacturing, yet the phenomenon of die shift during the compression molding process remains a significant challenge to yield and reliability.
Yu-Chi Sung   +7 more
doaj   +1 more source

Aplikasi kansei engineering untuk desain kemasan kopi excelsa Wonosalam

open access: yesAgrointek
Visual packaging attributes such as brand name, logo, color, packaging form, writing style and graphics are used for product identification and affect the buying decision (willing-to-buy).
Auditya Bisma   +2 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Innovative design of Hunan tea packaging under "traditional patterns + AI" model

open access: yesShipin yu jixie
This study investigates innovative packaging design approaches for Hunan tea under the "traditional patterns+AI" model. Utilizing Stable Diffusion model technology, this study creatively transforms embroidery patterns from Mawangdui silk textiles into ...
SHI Dandan, WAN Changlin, XIAO Yuqiang
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

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