Results 91 to 100 of about 236,786 (334)
Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Comparison and optimization of packet loss repair methods on VoIP perceived quality under bursty loss [PDF]
, 2002 Wenyu Jiang, Henning Schulzrinne
openalex +2 more sources
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
On dispersive energy transport and relaxation in the hopping regime
, 2000 A new method for investigating relaxation phenomena for charge carriers hopping between localized tail states has been developed. It allows us to consider both charge and energy {\it dispersive} transport.
A. N. Samukhin +24 more
core +1 more source
Uji Performansi Jaringan menggunakan Kabel UTP dan STP
Jurnal Elkomika, 2018 ABSTRAK Unshield Twisted Pair (UTP) dan Shield Twisted Pair (STP) merupakan tipe kabel untuk menghubungkan antar komputer sehingga dapat membentuk sebuah jaringan. Secara teori, maksimal panjang kabel yang diperbolehkan adalah 100 meter.
KUKUH NUGROHO, AHMAD YOGI KURNIAWAN
doaj +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Delay-Energy lower bound on Two-Way Relay Wireless Network Coding [PDF]
, 2014 Network coding is a novel solution that significantly improve the throughput and energy consumed of wireless networks by mixing traffic flows through algebraic operations. In conventional network coding scheme, a packet has to wait for packets from other
Chen, Wei, Zeng, Hongyi
core
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Mind the gap: void-creating algorithms for optical switching [PDF]
, 2015 With ever-increasing demand for bandwidth, optical packet/burst switching is proposed to utilize more of the available capacity of optical networks in the future.
Bruneel, Herwig +2 more
core +1 more source