Results 51 to 60 of about 255,219 (274)
Decomposition of multiple packings with subquadratic union complexity [PDF]
, 2016 Suppose $k$ is a positive integer and $\mathcal{X}$ is a $k$-fold packing of the plane by infinitely many arc-connected compact sets, which means that every point of the plane belongs to at most $k$ sets.
Pach, János, Walczak, Bartosz
core +2 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
A Landscape Analysis of Constraint Satisfaction Problems
, 2007 We discuss an analysis of Constraint Satisfaction problems, such as Sphere Packing, K-SAT and Graph Coloring, in terms of an effective energy landscape.
A. J. Liu +11 more
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Deterministic Distributed Edge-Coloring via Hypergraph Maximal Matching
, 2017 We present a deterministic distributed algorithm that computes a $(2\Delta-1)$-edge-coloring, or even list-edge-coloring, in any $n$-node graph with maximum degree $\Delta$, in $O(\log^7 \Delta \log n)$ rounds.
Fischer, Manuela +2 more
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
A list version of graph packing [PDF]
, 2015 We consider the following generalization of graph packing. Let $G_{1} = (V_{1}, E_{1})$ and $G_{2} = (V_{2}, E_{2})$ be graphs of order $n$ and $G_{3} = (V_{1} \cup V_{2}, E_{3})$ a bipartite graph.
Győri, Ervin +3 more
core +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Online Bin Packing with Advice [PDF]
, 2013 We consider the online bin packing problem under the advice complexity model where the 'online constraint' is relaxed and an algorithm receives partial information about the future requests.
Boyar, Joan +3 more
core +2 more sources