Results 61 to 70 of about 186,890 (225)

WEIGHTED-EDGE-COLORING OF k-DEGENERATE GRAPHS AND BIN-PACKING

open access: yes, 2011
The weighted-edge-coloring problem of an edge-weighted graph whose weights are between 0 and 1, consists in finding a coloring using as few colors as possible and satisfying the following constraints: the sum of weights of edges with the same color and ...
FLORIAN HUC, HUC, FLORIAN
core   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Packing chromatic number of transformation graphs

open access: yes, 2019
Graph coloring is an assignment of labels called colors to elements of a graph. The packing coloring was introduced by Goddard et al. [1] in 2008 which is a kind of coloring of a graph. This problem is NP-complete for general graphs.
Ozen Dortok H.B.   +3 more
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Coloring count cones of planar graphs [PDF]

open access: yes, 2022
For a plane near‐triangulation G with the outer face bounded by a cycle C, let nG⋆ denote the function that to each 4‐coloring ψ of C assigns the number of ways ψ extends to a 4‐coloring of G.
Lidicky, Bernard, Dvořák, Zdeněk
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

On S-Packing Coloring of Subcubic Graphs [PDF]

open access: yes
Given a sequence $S = (s_1, s_2, \ldots, s_k)$ of positive integers with $s_1 \leq s_2 \leq \ldots \leq s_k$, an $S$-packing coloring of a graph $G$ is a partition of $V(G)$ into $k$ subsets $V_1, V_2, \ldots, V_k$ such that for each $1 \leq i \leq k ...
Bazzal, Hadeel Al
core  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

S-Packing Coloring on Graphs

open access: yes, 2010
泛寬著色問題主要來自無線網路的頻道分配、資源配置及生物多樣性模型。舉例來說,為了避免互相干擾,美國聯邦通訊委員會規定廣播電台必須相隔足夠距離才能使用相同的頻率,因為物理的限制,不同頻率需要不同的距離,政府部門必須適當配置才能使整個廣播網絡順利運作。此問題化約成圖論型式:對於給定的有限遞增正整數數列$(s_1,s_2,dots,s_k)$及圖$G$,若我們能夠給予圖上的每個頂點一個顏色,使得著第$i$色的兩個相異頂點距離超過$s_i$,則稱此圖可被$(s_1,s_2,dots,s_k)$著色 ...
Chen, Sheng-Hua, 陳聖華
core  

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

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