Results 51 to 60 of about 186,890 (225)
The s-packing chromatic number of a graph [PDF]
, 2012 Let S = (a₁, a₂, ...) be an infinite nondecreasing sequence of positive integers. An S-packing k-coloring of a graph G is a mapping from V(G) to {1,2,...,k} such that vertices with color i have pairwise distance greater than $a_i$, and the S-packing ...
Xu, Honghai, Goddard, Wayne
core +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Extreme-Point-based Heuristics for the Three-Dimensional Bin Packing problem [PDF]
, 2008 One of the main issues in addressing three-dimensional packing problems is finding an efficient and accurate definition of the points at which to place the items inside the bins, because the performance of exact and heuristic solution methods is actually
CRAINIC T. G +3 more
core +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Dichotomies properties on computational complexity of S-packing coloring problems
, 2015 International audienceThis work establishes the complexity class of several instances of the S-packing coloring problem: for a graph G, a positive integer k and a non decreasing list of integers S = (s_1 , ..., s_k ), G is S-colorable, if its vertices ...
Gastineau, Nicolas
core +1 more source
(d, n)-packing coloring of generalized Sierpiński graphs [PDF]
, 2019 V magistrski nalogi so opisani grafi Sierpińskega in njihove posplošitve, (d, n)-pakirno barvanje grafov ter računsko iskanje (d, n)-pakirnih kromatičnih števil. Razvili smo algoritem za generiranje grafov Sierpińskega z osnovo 4 ter implementirali štiri
Jeromel, Anže
core
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source