Results 41 to 50 of about 24,121 (267)
Reinforcement learning based local search for grouping problems: A case study on graph coloring [PDF]
, 2016 Grouping problems aim to partition a set of items into multiple mutually disjoint subsets according to some specific criterion and constraints. Grouping problems cover a large class of important combinatorial optimization problems that are generally ...
Duval, Béatrice +2 more
core +5 more sources
Packing chromatic vertex-critical graphs
, 2019 The packing chromatic number $\chi_{\rho}(G)$ of a graph $G$ is the smallest integer $k$ such that the vertex set of $G$ can be partitioned into sets $V_i$, $i\in [k]$, where vertices in $V_i$ are pairwise at distance at least $i+1$.
Klavžar, Sandi, Rall, Douglas F.
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Decomposition of multiple packings with subquadratic union complexity [PDF]
, 2016 Suppose $k$ is a positive integer and $\mathcal{X}$ is a $k$-fold packing of the plane by infinitely many arc-connected compact sets, which means that every point of the plane belongs to at most $k$ sets.
Pach, János, Walczak, Bartosz
core +2 more sources
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Deterministic Distributed Edge-Coloring via Hypergraph Maximal Matching
, 2017 We present a deterministic distributed algorithm that computes a $(2\Delta-1)$-edge-coloring, or even list-edge-coloring, in any $n$-node graph with maximum degree $\Delta$, in $O(\log^7 \Delta \log n)$ rounds.
Fischer, Manuela +2 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Two new Probability inequalities and Concentration Results [PDF]
, 2010 Concentration results and probabilistic analysis for combinatorial problems like the TSP, MWST, graph coloring have received much attention, but generally, for i.i.d. samples (i.i.d. points in the unit square for the TSP, for example). Here, we prove two
Kannan, Ravindran
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source