Results 81 to 90 of about 116,760 (305)
Packing tripods: Narrowing the density gap
Discrete Mathematics, 2007 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
, 2019 The process of developing new compounds and materials is increasingly driven by computational modeling and simulation, which allow us to characterize candidates before pursuing them in the laboratory.
Mojtaba, Haghighatlari +4 more
core +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Bounds on packing density via slicing [PDF]
, 2014 This document is composed of a series of articles in discrete geometry, each solving a problem in packing density. • The first proves a local upper bound for the packing density of regular pentagons in R2.
Kusner, Wöden
core
The Experimental Study on Vibration Packing Density of Molecular Sieve
, 2011 The experiment studied granularity distributed from 1.3-3.0mm in the vibration loading process of molecular sieve, and the influence of all kinds of vibration parameters such as vibration frequency, vibration amplitude on the molecular sieve packing ...
Ming Xia Ge +3 more
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Shape influences on the packing density of frustums
, 2011 The shape of a frustum is a bivariate function of aspect ratio (w) and base radii ratio (c). To investigate the shape influences on the packing density of frustums, random packings of cones (c=0), truncated cones and cylinders (c=1) with various heights ...
Lingyi Meng +12 more
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FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
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