Results 111 to 120 of about 149,239 (310)

Packing and covering in higher dimensions

open access: yes, 2022
The present work surveys problems in $n$-dimensional space with $n$ large. Early development in the study of packing and covering in high dimensions was motivated by the geometry of numbers. Subsequent results, such as the discovery of the Leech lattice and the linear programming bound, which culminated in the recent solution of the sphere packing ...
openaire   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Tension modeling of package binding belts in cargo spacecraft

open access: yesMATEC Web of Conferences, 2018
At the site of cargo package binding in cargo spacecraft, the binding belt tension is loaded with a ratchet device. It is determined by experience of operators, therefore it’s difficult to quantify the force and the reliability of the binding belt is low.
Yuan Weifeng, Dai Hailin, Du Ruizhao
doaj   +1 more source

Residual Multiparticle Entropy for a Fractal Fluid of Hard Spheres

open access: yesEntropy, 2018
The residual multiparticle entropy (RMPE) of a fluid is defined as the difference, Δs, between the excess entropy per particle (relative to an ideal gas with the same temperature and density), sex, and the pair-correlation contribution, s2.
Andrés Santos   +2 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

An Adaptive Fitness-Dependent Optimizer for the One-Dimensional Bin Packing Problem [PDF]

open access: gold, 2020
Diaa Salama Abdul-Minaam   +3 more
openalex   +1 more source

Complex continued fractions with restricted entries

open access: yesElectronic Journal of Differential Equations, 1998
We study special infinite iterated function systems derived from complex continued fraction expansions with restricted entries. We focus our attention on the corresponding limit set whose Hausdorff dimension will be denoted by $h$. Our primary goal is to
Pawel Hanus, Mariusz Urbanski
doaj  

Multifractal Structure of Irregular Sets via Weighted Random Sequences

open access: yesFractal and Fractional
We study the multifractal structure of irregular sets arising from Fibonacci-weighted sums of sequences of random variables. Focusing on Cantor-type subsets Kε of the unit interval, we construct sequences of free and forced blocks, where the free blocks ...
Najmeddine Attia, Taoufik Moulahi
doaj   +1 more source

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