Results 111 to 120 of about 144,663 (264)
Multi-objective optimization in plastic injection molding with injection and packing time
Nihon Kikai Gakkai ronbunshu, 2015 Plastic injection molding (PIM) is one of the most important manufacturing processes for producing plastic products. The process parameters in the PIM, such as mold temperature, melt temperature, and injection pressure affect the product quality and the ...
Shinji NATSUME, Satoshi KITAYAMA
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Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
Molecular Oncology, EarlyView.In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza +3 more
wiley +1 more source
Complex continued fractions with restricted entries
Electronic Journal of Differential Equations, 1998 We study special infinite iterated function systems derived from complex continued fraction expansions with restricted entries. We focus our attention on the corresponding limit set whose Hausdorff dimension will be denoted by $h$. Our primary goal is to
Pawel Hanus, Mariusz Urbanski
doaj
Neural Development, 2017 Background The multiplex, lattice mosaic of cone photoreceptors in the adult fish retina is a compelling example of a highly ordered epithelial cell pattern, with single cell width rows and columns of cones and precisely defined neighbor relationships ...
Mikiko Nagashima +4 more
doaj +1 more source
On symplectic packing problems in higher dimensions
Mathematische AnnalenAbstract Let $$B^{2n}(R)$$ denote the closed 2n-dimensional symplectic ball of area R, and let $$\Sigma _g(L)$$ be a closed symplectic surface of genus g and area L. We prove that there is a symplectic embedding $$\bigsqcup \nolimits _{i=1}^k B^4(R_i) \times \Sigma _g (L) \
Kyler Siegel, Yuan Yao
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Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Molecular Oncology, EarlyView.We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf +10 more
wiley +1 more source