Results 71 to 80 of about 149,239 (310)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
An Effective Corner Increment-Based Algorithm for the Two-Dimensional Strip Packing Problem
IEEE Access, 2018 The 2-D strip packing problem is an NP-hard combinatorial optimization problem. Given a strip with fixed width and infinite height, the aim of strip packing is to pack a set of rectangles with known widths and heights into the strip such that the used ...
Zhen Chen, Jianli Chen
doaj +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Packing Multidimensional Spheres in an Optimized Hyperbolic Container
MathematicsThe problem of packing multidimensional spheres in a container defined by a hyperbolic surface is introduced. The objective is to minimize the height of the hyperbolic container under non-overlapping and containment conditions for the spheres ...
Yuriy Stoyan +6 more
doaj +1 more source
Further lattice packings in high dimensions [PDF]
Mathematika, 1982 Barnes and Sloane recently described a "general construction" for lattice packings of equal spheres in Euclidean space. In the present paper we simplify and further generalize their construction, and make it suitable for iteration. As a result we obtain lattice packings in U m with density A satisfying log2 A ~ — m logf m, as m -> oo, where logf m is ...
Bos, A., Conway, J. H., Sloane, N. J. A.
openaire +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
A φ-Contractivity and Associated Fractal Dimensions
Fractal and FractionalIn this paper, we extend the concept of dimension of sets to some general frameworks relative to a gauge function φ, where two simultaneous dimensions are introduced.
Nifeen H. Altaweel +2 more
doaj +1 more source
Use of genetic algorithms for solving problems of optimal cutting
ITM Web of Conferences, 2016 Cutting and packing problem is one of the most common optimization problem. Even a small space or material savings allow obtaining substantial advantages on an industrial scale. This paper proposes the genetic algorithm to solve this problem. It includes
Sergievskiy Maxim, Syroezhkin Sergey
doaj +1 more source
An analysis of heuristic templates in Genetic Programming for one-dimensional cutting and packing problems [PDF]
, 2023 Jesús Quesada +4 more
openalex +1 more source
, 2017 This paper investigates the algorithmic dimension spectra of lines in the Euclidean plane. Given any line L with slope a and vertical intercept b, the dimension spectrum sp(L) is the set of all effective Hausdorff dimensions of individual points on L. We
D Turetsky +11 more
core +1 more source