Results 111 to 120 of about 261,105 (346)

Ai-lncRNA EGOT enhancing autophagy sensitizes paclitaxel cytotoxicity via upregulation of ITPR1 expression by RNA-RNA and RNA-protein interactions in human cancer

open access: yesMolecular Cancer, 2019
The biology function of antisense intronic long noncoding RNA (Ai-lncRNA) is still unknown. Meanwhile, cancer patients with paclitaxel resistance have limited therapeutic options in the clinic.
Shouping Xu   +10 more
semanticscholar   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

open access: yesAdvanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Dose-dense weekly paclitaxel and carboplatin compared with conventional paclitaxel and carboplatin treatment for stage II-IV ovarian cancer patients

open access: yesBangladesh Journal of Pharmacology, 2015
We investigated dose-dense weekly paclitaxel and carboplatin compared with conventional paclitaxel and carboplatin treatment on stage II-IV ovarian cancer patients.
Zhenhua Du, Xiaolin Ma
doaj  

Cyclosporine A Decreased Paclitaxel Resistance in Prostate Cancer Cells by Inhibiting MTDH Expression

open access: yesAmerican Journal of Men's Health
This study aims to investigate the effect and mechanism of cyclosporine A (CsA) on paclitaxel-resistant prostate cancer cells. Paclitaxel-resistant prostate cancer cell lines were established by gradual increment method.
Jiangtao Li   +11 more
doaj   +1 more source

ANTIGENICITY STUDY OF PACLITAXEL

open access: yesThe Journal of Toxicological Sciences, 1994
The antigenic property of paclitaxel was examined using its protein mixtures (paclitaxel + OVA, paclitaxel + GSA, paclitaxel + RSA) in guinea pigs and mice in comparison with ovalbumin (OVA) and the protein conjugate of 4-aminoantipriyne (AAP). The following results were obtained: 1.
Katsumi Ishikawa   +4 more
openaire   +4 more sources

Engineering Aging: Approaches to Model and Deconstruct Biological Complexity

open access: yesAdvanced Materials, EarlyView.
The macro‐experiences of aging are the result of an accumulation of micro‐changes that occur over time. Abstract The disparity between the global increase in life expectancy and the steady decline in health outcomes with age has been a major driver for developing new ways to research aging.
Habib Joukhdar   +7 more
wiley   +1 more source

Analysis of exposure times and dose escalation of paclitaxel in ovarian cancer cell lines [PDF]

open access: bronze, 1994
Lisa Adler   +4 more
openalex   +1 more source

The dark side of paclitaxel [PDF]

open access: yesOncology Reviews, 2010
The bark extract of Pacific Yew (Taxus brevifolia) was first reported to have anti-tumor activity in 1963. The active constituent responsible for this activity was later identified in 1971 as paclitaxel [1]. Paclitaxel is a cytotoxic drug used in the treatment of variety of tumors including ovarian, breast, and non-small-cell lung cancers...
openaire   +2 more sources

Ultrasound-mediated Delivery of Paclitaxel for Glioma: A Comparative Study of Distribution, Toxicity, and Efficacy of Albumin-bound Versus Cremophor Formulations

open access: yesClinical Cancer Research, 2019
Purpose: Paclitaxel shows little benefit in the treatment of glioma due to poor penetration across the blood–brain barrier (BBB). Low-intensity pulsed ultrasound (LIPU) with microbubble injection transiently disrupts the BBB allowing for improved drug ...
Daniel Y. Zhang   +16 more
semanticscholar   +1 more source

Ultrashort‐Pulsed Laser Diffusion Enhancement in Liquids for Cold Extraction of Coffee in an Analytically Validated Low‐Fluence Regime

open access: yesAdvanced Photonics Research, EarlyView.
In this article, pulsed laser diffusion enhancement in liquids as an analytically validated laser extraction in liquids method of coffee suspensions in a defined low fluence window is presented. The results confirm the generation of a unique aroma profile and reduced acidity, which is neither attributed to changes in the specific surface area nor ...
Tina Friedenauer   +15 more
wiley   +1 more source

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