Results 131 to 140 of about 163,661 (247)

A randomized, open-label, two-way crossover clinical trial to evaluate the food effect on pharmacokinetics and safety of DHP107 in patients with advanced solid tumors: the FEEL study. [PDF]

Cancer Chemother Pharmacol
Hitre E, Láng I, Páll D.
europepmc   +1 more source

Recent advances and clinical applications of 3D printing for female reproductive organ regeneration and gynecological disease

Interdisciplinary Medicine, EarlyView.
This comprehensive review highlights the transformative role of 3D printing and bioprinting technologies in the regeneration of female reproductive organs and the treatment of gynecological diseases. Unlike previous overviews that focus narrowly on isolated applications, this work provides an integrative analysis of recent clinical and preclinical ...
Chan Hum Park, In‐Sun Hong
wiley   +1 more source

Toward Sustainable Paclitaxel Bioproduction: Plant Biology, Biosynthesis and Platform Engineering. [PDF]

Plants (Basel)
Zhang M, Xing X, Zhu H.
europepmc   +1 more source

Reversing brain aging: Targeting energy metabolism in endogenous neural stem cells

Interdisciplinary Medicine, EarlyView.
Mechanism of endogenous neural stem cells (eNSCs) energy metabolism disorder leading to brain aging and targeted eNSCs intervention strategies (By biorender). The disorder of energy metabolism of eNSCs can lead to their resting and aging, and eventually lead to brain aging.
Chong Chen, Jiayi Wang, Jimin Yu, Yiran Zhou, Lihai Liu, Jing Liu, Liang Wang   +6 more
wiley   +1 more source

Prognostic associations between patient-reported outcomes and overall survival among patients with advanced squamous non-small cell lung cancer: results from the RATIONALE-307 trial. [PDF]

Qual Life Res
Wang J, Yu X, Leaw S, Barnes FB, Victor T, Barnes G.   +5 more
europepmc   +1 more source

Mitochondria‐targeted nanomedicine for cancer therapy: Targeting strategies, therapeutic mechanisms, and translational challenges

Interdisciplinary Medicine, EarlyView.
This review highlights recent advances in mitochondria‐targeted nanomedicine for cancer therapy. It summarizes key targeting strategies and delineates four principal therapeutic mechanisms: oxidative stress–induced mitochondrial dysfunction, disruption of energy metabolism, direct mitochondrial damage, and induction of immunogenic cell death.
Linfeng Xiao, Xiaowei Chang, Jun Zhang, Yinshan Hong, Wenhui Cao, Zhewu Zhao, Yu‐E. Wang, Yanling Yang   +7 more
wiley   +1 more source

Retraction: Biogenic green synthesis of MgO nanoparticles using Saussurea costus biomasses for a comprehensive detection of their antimicrobial, cytotoxicity against MCF-7 breast cancer cells and photocatalysis potentials. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

The 5R's of large language model‐assisted diagnosis: A practical framework for hospitalists

Journal of Hospital Medicine, EarlyView.
Abstract Diagnostic error remains a major patient safety challenge in hospital medicine. Large language models (LLMs) are increasingly used by clinicians to aid in diagnosis, yet most lack a structured approach for doing so safely and effectively. In this piece, we propose a practical, clinician‐centered framework for LLM‐assisted diagnosis.
Peter Barish, Andrew D. Auerbach, Sumant R. Ranji   +2 more
wiley   +1 more source

Limited Immune-Mediated Efficacy of Anti-PD-L1/VEGF in EGFR-TKI-Naïve <i>Egfr</i>-Mutant Lung Cancer with Non-Inflamed Tumor Microenvironment. [PDF]

Curr Oncol
Hirabae A, Kuribayashi T, Tomida S, Okawa S, Nakasuka T, Nishii K, Nishimura J, Makimoto G, Ninomiya K, Higo H, Rai K, Ichihara E, Hotta K, Sugimoto M, Togashi Y, Maeda Y, Kiura K, Ohashi K.   +17 more
europepmc   +1 more source

Durable Cancer Control and Extended Long‐Term Survival Following Salvage Surgery for Squamous Cell Carcinoma of the Anal Canal: A Cohort Study

Journal of Surgical Oncology, EarlyView.
ABSTRACT Aim Salvage surgery is the standard‐of‐care for patients with squamous cell carcinoma of the anal canal (SCCa) who experience isolated locoregional failure after upfront chemoradiotherapy. While perioperative morbidity and short‐term survival outcomes have been described, long‐term outcomes of surgical salvage are unknown.
Paul Savage, David P. Cyr, Dan E. Schiller, Bernard J. Cummings, Alexandra M. Easson, Andrew J. Smith, Carol J. Swallow   +6 more
wiley   +1 more source