Results 171 to 180 of about 281,052 (341)

REPRODUCTIVE AND DEVELOPMENTAL TOXICITY STUDIES OF PACLITAXEL (I) : Intravenous administration to rats prior to and in the early stages of pregnancy

, 1994
S Kai, Hisashi KOHMURA, E Hiraiwa, S Koizumi, K Ishikawa, Shigeo Kawano, Kohji KUROYANAGI, Norimichi Hattori, H Chikazawa, Hiroshi Kondoh   +9 more
openalex   +2 more sources

Cascade‐Targeted Nanoparticles for Enhanced Gemcitabine Delivery and Adenosine Metabolism Modulation to Overcome Treatment Resistance in Pancreatic Cancer

Advanced Science, EarlyView.
The aberrant adenosine metabolism leads to chemoresistance and immunosuppressive microenvironment. A versatile albumin‐polyplexes conjugated nanoparticle B‐PDEA@CPA is prepare for the codelivery of gemcitabine and siCD39. The nanoparticle releases gemcitabine‐loaded albumin upon microenvironment to achieve promoted penetration and cellular uptake ...
Hongrui Fan, Hongyi Chen, Haolin Song, Chufeng Li, Yu Wang, Zhenhao Zhao, Qin Guo, Xuwen Li, Mingxuan Liu, Tao Sun, Chen Jiang   +10 more
wiley   +1 more source

TOXICITY STUDIES OF PACLITAXEL (III) : Six-month intermittent intravenous toxicity in rats

, 1994
T. Kadota, Hiroshi Kondoh, H Chikazawa, Kohji KUROYANAGI, Norimichi Hattori, K Ishikawa, Shigeo Kawano, K Sakakura, S Koizumi, E Hiraiwa   +9 more
openalex   +2 more sources

Nature‐Inspired Nanostructures from Multiple‐Species Biomembranes: Rational Engineering and Therapeutic Applications in Tumor‐Targeted Nanomedicine

Advanced Science, EarlyView.
Naturally derived biomembrane nanostructures by mimicking evolutionarily optimized biological architectures could effectively suppress tumor growth and have emerged as a compelling strategy in translational biomedicine. This review provides a systematic overview of rational design and underlying antitumor therapeutic mechanisms of mammalian cells ...
Xiaodan Wei, Chi Wang, Xiangyan Chen, Yuanyuan Zhu, Mei Yang, Ningxi Li, Honglin Huang, Guangjian Zhang, Mingzhen Zhang, Yiyao Liu, Rui Gao   +10 more
wiley   +1 more source

Pharmacokinetic evaluation of paclitaxel, albumin-binding paclitaxel, and liposomal-encapsulated albumin-binding paclitaxel upon gastric subserosal administration

Frontiers in Pharmacology
Introduction: Systemic chemotherapy is typically administered following radical gastrectomy for advanced stage. To attenuate systemic side effects, we evaluated the effectiveness of regional chemotherapy using paclitaxel, albumin-paclitaxel, and liposome-
Yoontaek Lee, Sun Mi Park, In Ho Song, Bom Sahn Kim, Hyun Soo Park, Hyun Soo Park, Hyun Soo Park, Byung Seok Moon, Hyung-Ho Kim   +8 more
doaj   +1 more source

Salvage esophagectomy for unresectable locally advanced esophageal squamous cell carcinoma: Significant or not?

Annals of Gastroenterological Surgery, EarlyView.
Abstract We reviewed the current status and perspectives on salvage esophagectomy for initially unresectable locally advanced esophageal squamous cell carcinoma (ESCC) in the era of minimally invasive surgery and immunotherapy. Although the standard treatment for these patients is definitive chemoradiotherapy (CRT), the complete response rate to CRT ...
Hiroshi Saeki, Makoto Sakai, Takayoshi Watanabe, Makoto Sohda, Ken Shirabe   +4 more
wiley   +1 more source

Determination of New Anticancer Drug, Paclitaxel, in Biological Fluids by High Performance Liquid Chromatography

, 1994
Hajime MASE, Masaki Hiraoka, Atsushi Suzuki, H Nakanomyo   +3 more
openalex   +2 more sources

Microtubule-disrupting agents inhibit nitric oxide production in murine peritoneal macrophages stimulated with lipopolysaccharide or paclitaxel (Taxol) [PDF]

, 1996
Teruo Kirikae, Fumiko Kirikae, Yoichi Oghiso, Masayasu Nakano   +3 more
openalex   +1 more source

Survival Outcomes of Esophageal Squamous Cell Carcinoma Patients Who Underwent Salvage Esophagectomy: A Literature Review and Results From Two High‐Volume Centers

Annals of Gastroenterological Surgery, EarlyView.
This study aimed to investigate survival outcomes, the efficacy of lymph node (LN) dissection, and recurrence patterns in 69 patients who underwent R0 salvage surgery for esophageal squamous cell carcinoma. Of note, abdominal LN metastases had a negative impact on survival in our series.
Kotaro Sugawara, Koichi Yagi, Takashi Fukuda, Shoh Yajima, Daiji Oka, Yoshiyuki Miwa, Shuichiro Oya, Asami Okamoto, Raito Asaoka, Yoshifumi Baba   +9 more
wiley   +1 more source

First line chemotherapy with carboplatin plus paclitaxel in advanced ovarian cancer - a new standard of care? [PDF]

, 1999
Andreas du Bois, J.P. Neijt, J.T. Thigpen   +2 more
openalex   +1 more source