Disruption of microtubules with low intensity ultrasound rescues hair follicle damage by paclitaxel [PDF]
Xiang‐Xi Xu +4 more
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Macromolecular Rapid Communications, EarlyView.Mono‐ and bivalent‐, alanine‐modified poly‐iso‐butylenes, folding into beta‐sheets, were prepared by living carbocationic polymerization and subsequent endgroup modification. These PIB‐conjugates are useful as solid polymers for the drug release of triamcinolone and nimodipine. ABSTRACT Poly‐iso‐butylene (PIB) is a well known biocompatible polymer with
Philipp S. Hilgeroth +2 more
wiley +1 more source
A Non‐Antigenic Randomized Polyethylene Glycol/Poly(2‐Phenyl‐2‐Oxazine)‐Based Drug Delivery Platform
Macromolecular Rapid Communications, EarlyView.Randomized PEG (rPEG), a conceptually new PEG alternative, is combined with poly(2‐phenyl‐2‐oxazine) (PPheOzi) to establish an rPEG‐b‐PPheOzi‐b‐rPEG micellar drug delivery platform. The PPheOzi block enables high drug loadings, while competitive ELISA reveals a drastic reduction in anti‐PEG antibody affinity of rPEG in comparison to PEG.
Julian Schmidt +6 more
wiley +1 more source
Synergistic anti-tumor effects of novel two-domain soluble Fms-like tyrosine kinase-1 and paclitaxel on three-dimensional breast cancer models: implications for targeted therapy. [PDF]
J Transl MedMutahar AZI, Dayal R, Salimath BP.
europepmc +1 more source
Protein glycosylation in lung cancer from a mass spectrometry perspective
Mass Spectrometry Reviews, EarlyView.Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi +2 more
wiley +1 more source
Paclitaxel- and Sirolimus-Coated Balloons Versus Drug-Eluting Stents in Coronary Artery Disease: A Comprehensive Narrative Review. [PDF]
Life (Basel)Gherasie FA +4 more
europepmc +1 more source
Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking
Mass Spectrometry Reviews, EarlyView.ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu +4 more
wiley +1 more source
Paclitaxel-Induced Hypertriglyceridemia Complicated by Acute Pancreatitis: A Case Report. [PDF]
CureusChowdhary R +5 more
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In vitro analysis of ovarian cancer response to cisplatin, carboplatin, and paclitaxel identifies common pathways that are also associated with overall patient survival [PDF]
, 2012 Elona Biçaku +14 more
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Machine Learning for Predictive Modeling in Nanomedicine‐Based Cancer Drug Delivery
Med Research, EarlyView.The integration of AI/ML into nanomedicine offers a transformative approach to therapeutic design and optimization. Unlike conventional empirical methods, AI/ML models (such as classification, regression, and neural networks) enable the analysis of complex clinical and formulation datasets to predict optimal nanoparticle characteristics and therapeutic
Rohan Chand Sahu +3 more
wiley +1 more source