Results 61 to 70 of about 25,619 (306)

Enhancing CAR‐T Cell Efficacy in Solid Tumors by Inhibiting CCL5/VEGF‐Mediated Angiogenesis

open access: yesAdvanced Science, EarlyView.
This study reveals that CAR‐T cells in solid tumors produce CCL5, which paradoxically induces VEGF and angiogenesis to promote tumor growth. Blocking CCL5/VEGF signaling—through gene knockout, or the CCR5 inhibitor maraviroc—significantly enhances the antitumor efficacy of CAR‑T therapy (the diagram was created in Biorender).
Shishuo Sun   +15 more
wiley   +1 more source

Feeding Rate of Soil Animals in Different Ecosystems in Pati, Indonesia

open access: yesHayati Journal of Biosciences, 2006
The feeding activity of soil animals was measured by using bait lamina test in three main ecosystems, i.e. the teak forest, home garden and rainfed paddy field. Two additional ecosystems in rainfed paddy field, i.e.
RAHAYU WIDYASTUTI
doaj   +3 more sources

Research on Soil Heavy Metal Accumulation and Chemical Environmental Quality Evaluation Based on Environment Law

open access: yesChemical Engineering Transactions, 2017
In this paper, it gives research on annual net flux and accumulative amount of the soil heavy mental in the Pearl River Basin on the basis of giving full consideration to environment law, by adopting such methods as theoretical calculation and field test
Nan Qi, Xin Zhang
doaj   +1 more source

Research perspectives on paddy field systems: ecological functions and environmental impacts

open access: yesInternational Journal of Agricultural Sustainability, 2020
Paddy is an important artificial wetland ecosystem related to sustainable development of agriculture and environment. According to 12,276 paddy-related publications in SCIE database during 1997–2016, this study revealed the global paddy research trends ...
Yanhua Zhuang   +3 more
doaj   +1 more source

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon   +21 more
wiley   +1 more source

Ecotoxicology of pesticides in the tropical paddy field ecosystem

open access: yes, 2021
In tropical countries rice has been identified as one of the crops that is particularly susceptible to the negative impacts of pesticide use. In addition to the physicochemical nature of the pesticide, tropical climatic conditions and agricultural ...
Matin, Malek A.   +4 more
core  

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

open access: yesAdvanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann   +11 more
wiley   +1 more source

Buried Unstrained Germanium Channels: A Lattice‐Matched Platform for Quantum Technology

open access: yesAdvanced Science, EarlyView.
ABSTRACT Strained germanium (ε$\varepsilon$‐Ge) and strained silicon (ε$\varepsilon$‐Si) buried quantum wells have enabled advanced spin‐qubit quantum processors. However, in the absence of suitable lattice‐matched substrates, ε$\varepsilon$‐Ge and ε$\varepsilon$‐Si are deposited on defective, metamorphic SiGe buffers, which may impact device ...
Davide Costa   +10 more
wiley   +1 more source

Studies on the Radiation Balance in the Paddy Field and Water Temperature in the Percolating Paddy Field

open access: yesJournal of Agricultural Meteorology, 1960
In order to research the radiation balance in the paddy field and the relation between water temperature in the percolating paddy field to percolation, the author carried out the observations of the radiation, water temperature, percolation in August 1958 at Nyuzen, Toyama Pref.The radiations were measured by using Beckman's net radiometer ...
openaire   +2 more sources

A Conserved DT2‐bZIP66‐NF‐YC4 Regulatory Module Confers Drought Tolerance in Rice and Arabidopsis

open access: yesAdvanced Science, EarlyView.
This study identifies a conserved tripartiteDT2–bZIP66–NF‐YC4 transcriptional module that enhances rice drought tolerance by activating stress‐responsive genes. This regulatory complex is functionally conserved across cereals and Arabidopsis, providing promising targets for engineering drought‐resilient crops. ABSTRACT Drought stress severely restricts
Jun Shen   +18 more
wiley   +1 more source

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