Results 71 to 80 of about 371,290 (294)

Foundation Paediatric Pharmacy Workbook [PDF]

open access: yes, 2021
The Foundation Paediatric Pharmacy Workbook has been developed as a national resource by the Neonatal and Paediatric Pharmacists Group (NPPG) to support paediatric pharmacy practice throughout the UK.
Khan, F.
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Association for European Paediatric and Congenital Cardiology recommendations for basic training in paediatric and congenital cardiology 2020

open access: yes, 2020
The recommendations of the Association for European Paediatric and Congenital Cardiology for basic training in paediatric and congenital cardiology required to be recognised as a paediatric cardiologist by the Association for European Paediatric and ...
Blom, Nico A.   +19 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Comparison between macintosh, miller and mccoy laryngoscope blade size 2 in paediatric patients – A randomised controlled trial

open access: yesIndian Journal of Anaesthesia, 2019
Background and Aims: Paediatric airway needs special consideration as it is not a miniature replica of adult airway, rather it has different anatomy with different proportion and angulations.
Pratishtha Yadav   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Stamps in paediatrics

open access: yesArchives of Disease in Childhood, 2000
Over the next months the Archives of Disease in Childhood and the Fetal and Neonatal edition will feature a series of “Stamps in paediatrics”. Postage stamps and cancellation marks provide an excellent advertising medium, which has been fully utilised over the years in promoting health care and public …
M K, Davies, A J, Mayne
openaire   +3 more sources

Adherence to medical regimen after paediatric liver transplantation: a systematic review and meta-analysis

open access: yesPatient Preference and Adherence, 2018
Xingchu Meng, Wei Gao, Kai Wang, Chao Han, Wei Zhang, Chao Sun Department of Organ Transplantation, Tianjin First Center Hospital, Tianjin, China Purpose: Adherence to the medical regimen after pediatric liver transplantation is crucial for good ...
Meng X   +5 more
doaj  

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