Results 31 to 40 of about 2,010 (167)

Integrating network pharmacology analysis and pharmacodynamic evaluation for exploring the active components and molecular mechanism of moutan seed coat extract to improve cognitive impairment

Frontiers in Pharmacology, 2022
Paeonia suffruticosa (Moutan) is a traditional medicinal plant in China. Its seed coat is rich in resveratrol oligomer, especially suffruticosol B (SB).
Yue Wang, Xinyan Wu, Kailin Yang, Qing Liu, Baoping Jiang, Runmei Yang, Peigen Xiao, Chunnian He   +7 more
doaj   +1 more source

Moutan Cortex Extract Mediates Diabetic Retinopathy by Blocking the ROS‑Triggered HIF‐1α/VEGF Axis in Retinal Pigment Epithelial Cells

eFood, Volume 7, Issue 4, August 2026.
Schematic diagram of the mechanism by which Moutan Cortex extract (MCE) ameliorates DR. MCE alleviates retinal structural damage and reduces neovascular lesions by downregulating the ROS/HIF‐1α/VEGF signaling axis. ABSTRACT Moutan Cortex is a functional food ingredient with multiple health benefits, but its effects on diabetic retinopathy (DR) remain ...
Mei‐rong Li, Xian‐yi Zhang, Wan‐ying Zhang, Nan Chen, Wei‐wei Lv, Tian‐yu Liu, Xu Guo, Ying‐ying Chen, Meng‐qi Zhang, Shu‐tao Sun, Mu‐xuan Wang, Qi‐dong Ren, Chao Liu, Jin‐yue Sun   +13 more
wiley   +1 more source

Paeoniflorin alleviates 17α-ethinylestradiol-induced cholestasis via the farnesoid X receptor-mediated bile acid homeostasis signaling pathway in rats

Frontiers in Pharmacology, 2022
Cholestasis, characterized by disturbance of bile formation, is a common pathological condition that can induce several serious liver diseases. As a kind of trigger, estrogen-induced cholestasis belongs to drug-induced cholestasis.
Rulin Wang, Rulin Wang, Tengteng Yuan, Tengteng Yuan, Jing Sun, Menghuan Yang, Menghuan Yang, Yunna Chen, Yunna Chen, Lei Wang, Lei Wang, Yanyan Wang, Yanyan Wang, Weidong Chen, Weidong Chen, Daiyin Peng, Daiyin Peng   +16 more
doaj   +1 more source

Paeonol as a Multi‐Target Therapy for Neurological Disorders: Mechanistic Insights Into Neuroprotection

Immunity, Inflammation and Disease, Volume 14, Issue 8, August 2026.
Paeonol (PNL) exhibits neuroprotective effects by reducing oxidative stress, neuroinflammation, and apoptosis. It enhances antioxidant defenses (SOD and GSH), inhibits pro‐inflammatory pathways (NF‐κB and TLR4), and modulates apoptotic proteins (Bcl‐2 and Bax).
Md. Sakib Al Hasan, Naznin Shahria, Yasin Emon, Mohammad Y. Alshahrani, Emon Mia, Faisal H. Altemani, Rituparna Biswas Suma, Umme Habiba Sumaya, Mohammed Burhan Uddin, Md. Torequl Islam   +9 more
wiley   +1 more source

Assessing ChatGPT for taxonomic and floristic studies

Nordic Journal of Botany, Volume 2026, Issue 8, August 2026.
The advancement of biological sciences has long been closely linked to technological progress. ChatGPT, a generative artificial intelligence chatbot capable of producing human‐like conversational responses, has recently attracted attention as a potential support tool for scientific research.
Mykyta Peregrym, Olena Kozak, Ahmet Emre Yaprak, Alan Elliott, Pedro Bond Schwartsburd, Karime Abidkulova, Anna Voytsekhovich, Olena Danylevska   +7 more
wiley   +1 more source

A new phenone from the roots of Paeonia suffruticosa Andrews [PDF]

Natural Product Research, 2016
Thirteen phenones were obtained from the 70% ethanol extract of Paeonia suffruticosa Andrews. Their structures were determined on the basis of chemical methods and spectral data. Among them, compound 1 was identified as a new compound, and compounds 5 and 13 were obtained from genus Paeonia for the first time.
Liqin, Ding, Qingfei, Zuo, Dandan, Li, Xinchi, Feng, Xiumei, Gao, Feng, Zhao, Feng, Qiu   +6 more
openaire   +2 more sources

Quality Evaluation of Tree Peony and Herbaceous Peony Flower Teas Made from Different Cultivars [PDF]

Shipin Kexue
To evaluate the potential of tree peony (Paeonia suffruticosa) and herbaceous peony (Paeonia lactiflora) germplasm resources for flower tea development and to enrich the variety of flower tea products, 15 tree peony cultivars and 17 herbaceous peony ...
ZHANG Yingying, ZHANG Kaixin, WANG Haoren, ZHAO Liyuan, HAN Xueying, CHENG Chen, LI Ruicheng, ZHANG Yanlong, SHI Qianqian
doaj   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, Volume 40, Issue 8, Page 4759-4791, August 2026.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Paeoniflorin, a Natural Product With Multiple Targets in Liver Diseases—A Mini Review

Frontiers in Pharmacology, 2020
Paeoniflorin is derived from Paeonia suffruticosa Andr., Paeonia lactiflora Pall., or Paeonia veitchii Lynch and has been used in traditional medical applications for more than 2,000 years.
Xiao Ma, Wenwen Zhang, Yinxiao Jiang, Jianxia Wen, Jianxia Wen, Shizhang Wei, Shizhang Wei, Yanling Zhao   +7 more
doaj   +1 more source

Research on the Mechanism of Natural Products Acting on Chronic Obstructive Pulmonary Disease

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
This figure illustrates that approximately 80 natural compounds exert therapeutic effects against chronic obstructive pulmonary disease by targeting pathological mechanisms such as airway inflammation, oxidative stress, airway remodeling, mucus hypersecretion, emphysema, protease–antiprotease imbalance, apoptosis, and autophagy.
Shuna Wei, Xiaoju Liu
wiley   +1 more source