Results 131 to 140 of about 117,142 (268)
Cortical responses to balance perturbations persist without active postural control
Abstract figure legend A robotic balance simulator was used to test whether cortical responses to balance perturbations are contingent on active balance control or instead reflect the detection of unexpected motion. Participants experienced identical support‐surface rotations (toes‐up and toes‐down) while actively controlling balance or while being ...
Daphne N. R. Jansen +3 more
wiley +1 more source
Abstract Atrial fibrillation (AF), the most common clinical arrhythmia, is driven by inflammatory activation and oxidative stress, though precise molecular links remain unclear. This study identifies the P2X7 receptor as a key upstream regulator orchestrating proarrhythmic atrial remodeling through reactive oxygen species (ROS)‐mediated mitogen ...
Lingnan Zhang, Yeran Zhu, Xinshun Gu
wiley +1 more source
Targeting EZH2 in Cancer: From Molecular Mechanisms to Clinical Translation
The abnormal overexpression or gain‐of‐function mutations of EZH2 play a significant role in cancer occurrence and progression, highlighting the importance and potential of EZH2 as a cancer biomarker. Therefore, screening for effective and safe small‐molecule inhibitors, degraders, and natural compounds targeting EZH2 through preclinical cancer models ...
Xi Zhong +4 more
wiley +1 more source
We generated Thy1‐Cre–driven GCaMP8 transgenic rats by mating Thy1‐Cre rats with knock‐in rats carrying a floxed GCaMP8‐STOP cassette in the β‐actin locus. Robust neuronal GCaMP8 expression enabled transcranial calcium imaging of the auditory cortex, establishing this model as a powerful tool for minimally invasive cortical macro‐imaging and functional
Manavu Tohmi +10 more
wiley +1 more source
Platelet Activating Factor Acetyl Hydrolase (PAF AH) or LpPLA2 is a key enzyme in myocardial infarction catalyzes the sn-2 acetyl group of Platelet Activating Factor (PAF) into lyso PAF and acetate as non-potent inflammatory molecules ...
Jayarani Fatimah Putri +2 more
doaj
Development and Validation of the Professional Self‐Concept Scale for Hospital Nurses (PSCS‐HN)
ABSTRACT Professional self‐concept (PSC) has a positive influence on the attitudes and behaviors of members of an organization toward their work. Although establishing PSC is vital for nurses to provide quality nursing care, assessing PSC precisely in ever‐changing healthcare environments can be challenging.
Eun‐Ha Kim, Hye‐Ah Yeom
wiley +1 more source
ABSTRACT Mealtime assistance for people living with dementia presents care‐related challenges, yet few validated instruments assess nursing staff perspectives. This study developed and conducted an exploratory validation of the Assisting Mealtime Scale.
Hansen Tang +4 more
wiley +1 more source
ABSTRACT Climate change poses a significant threat to human health and is linked to various direct and indirect outcomes, including infectious diseases, heat‐related illnesses, and other climate‐sensitive conditions. However, standardized tools assessing perceived knowledge and awareness of climate‐related health effects remain limited.
Taha Gökmen Ülger +4 more
wiley +1 more source
PAF Triggered Pyroptotic NETosis Aggravates Myocardial Ischemia/Reperfusion Injury
Platelet activating factor (PAF) secreted by cardiomyocytes during MI/R, drives NETs formation and subsequent NETosis. PAF/NETosis signaling activation is an initiative and causal factor in driving MI/R injury. This study identifies dapagliflozin as a potent NETosis inhibitor, and demonstrates that manipulating PAF‐NETosis signal by dapagliflozin or ...
Jiawei Wu +11 more
wiley +1 more source
Reliability and Validity of the Chinese Version of the Premenstrual Symptoms Screening Tool
The Chinese PSST was validated in 1366 female college students. It showed excellent reliability and validity, effectively distinguishing PMS/PMDD from healthy controls with a stable two‐factor structure. ABSTRACT Objective To evaluate the reliability and validity of the Chinese version of the Premenstrual Symptoms Screening Tool (PSST) in a sample of ...
Xue Li, Xiaochun Wang
wiley +1 more source

