Results 41 to 50 of about 1,111,262 (342)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Frontiers in NutritionBackgroundSince wheat varieties and breeding lines developed by plant breeders in the western Himalayan region (Kashmir) have received limited attention with respect to their physical and protein quality characterization, the focus of the study is to ...
Taha Mukhtar +8 more
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Improved PageRank Algorithm Based on User Behavior and Page Analysis [PDF]
Jisuanji gongcheng, 2016 In classical PageRank algorithm,transition probability of page is equally distributed to the outlinks.There are few links of new page,so its PR value is generally low.Classical PageRank algorithm is used to calculate the PR value through links,without ...
WANG Xuyang,REN Guosheng
doaj +1 more source
'Exhibition of Industry of All Nations in 1851' [PDF]
, 2012 Page number(s) as given: pp.146 ...
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Local and Union Page Numbers [PDF]
, 2019 We introduce the novel concepts of local and union book embeddings, and, as the corresponding graph parameters, the local page number ${\rm pn}_\ell(G)$ and the union page number ${\rm pn}_u(G)$. Both parameters are relaxations of the classical page number ${\rm pn}(G)$, and for every graph $G$ we have ${\rm pn}_\ell(G) \leq {\rm pn}_u(G) \leq {\rm pn}(
Merker, Laura, Ueckerdt, Torsten
openaire +2 more sources
'A Looking-Glass for London - No. XXX London Extremes - Hyde Park and Rag Fair' [PDF]
, 2012 Page number(s) as given: pp.497 ...
core
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source