Results 51 to 60 of about 12,787,233 (297)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

The Lee spectral sequence, unknotting number, and the Knight Move Conjecture [PDF]

open access: yesTopology and its Applications, 2017
We show that the page at which the Lee spectral sequence collapses gives a bound on the unknotting number, u(K). In particular, for knots with u(K)
Akram Alishahi, Nathan Dowlin
semanticscholar   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Understanding the success of Page's model and related empirical equations in fitting experimental data of diffusion phenomena in food matrices

open access: yes, 2017
Page's equation is one of the most successful empirical equations applied to describe water migration throughout food drying processes. However, when analyzed in detail, the mathematical derivation shows a number of inconsistencies.
R. Simpson   +4 more
semanticscholar   +1 more source

Variability in grain, flour, functional properties and protein profiling in newly developed wheat genotypes grown in temperate climate of Western Himalayas

open access: yesFrontiers in Nutrition
BackgroundSince wheat varieties and breeding lines developed by plant breeders in the western Himalayan region (Kashmir) have received limited attention with respect to their physical and protein quality characterization, the focus of the study is to ...
Taha Mukhtar   +8 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Phylogenetic relationships of some Egyptian soybean cultivars (Glycine max L.) using SCoT marker and protein pattern

open access: yesBulletin of the National Research Centre, 2019
Background Electrophoretic SDS-PAGE and SCoT-PCR techniques were used to study the fingerprints and genetic diversity of six Egyptian soybean (Glycine max L.) genotypes (Giza111, Giza21, Giza82, Giza35, Giza22, and Giza83).
Walaa A. Rayan, Samira A. Osman
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Evaluation of Spam Impact on Arabic Websites Popularity

open access: yesJournal of King Saud University: Computer and Information Sciences, 2015
The expansion of the Web and its information in all aspects of life raises the concern of how to trust information published on the Web especially in cases where publisher may not be known.
Mohammed N. Al-Kabi   +2 more
doaj   +1 more source

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