Results 41 to 50 of about 10,132,612 (315)

On Page Number of N-free Posets

open access: yesElectronic Notes in Discrete Mathematics, 2006
Abstract In this paper we deal with the page number of partially ordered sets (posets). In particular, we find the page number of some N -free posets whose root graphs form a family of planar posets with known page number.
Anna Beata Kwiatkowska, Maciej M. Syslo
openaire   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Investigation of Women’s Health on Wikipedia—A Temporal Analysis of Women’s Health Topic

open access: yesInformatics, 2020
New health-related concepts, terms, and topics emerge, and the meanings of existing terms and topics keep changing. This study investigated and explored the evolutions of the women’s health topic on Wikipedia.
Yanyan Wang, Jin Zhang
doaj   +1 more source

Thermodynamics curvature in phase transitions for AdS black hole

open access: yesPhysics Letters B, 2021
We investigate the thermodynamic curvature in the Hawking-Page phase transition and the second-order phase transition of the AdS black hole. It is shown that the thermodynamic curvature has the same behavior in these two different phase transitions ...
Zhen-Ming Xu, Bin Wu, Wen-Li Yang
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Clinical Impact and Healthcare Resource Utilization Associated with Early versus Late COPD Diagnosis in Patients from UK CPRD Database [Corrigendum]

open access: yesInternational Journal of COPD, 2020
Kostikas K, Price D, Gutzwiller FS, et al. Int J Chron Obstruct Pulmon Dis. 2020;15:1729–1738. On page 1730 in Patients and Methods, Study Design section, and on page 1736 Ethics Approval section, the ISAC number reported was ...
Kostikas K   +8 more
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy