Results 81 to 90 of about 12,787,233 (297)

An Approach to Page Ranking Based on Discourse Structures

open access: yesJournal of Communications Software and Systems, 2016
World Wide Web (WWW) which is predominant source for Information Retrieval today (IR) is essentially a set of hyperlinked documents. A web page containing more number of related hyperlinks satisfy the user needs in a single page.
Subalalitha Chinnaudayar Navaneethakrishnan   +1 more
doaj  

A New Algorithm for Detecting GPN Protein Expression and Overexpression of IDC and ILC Her2+ Subtypes on Polyacrylamide Gels Associated with Breast Cancer

open access: yesAlgorithms
Sodium dodecyl sulfate–polyacrylamide gel electrophoresis (SDS-PAGE) is used to identify protein presence, absence, or overexpression and usually, their interpretation is visual.
Jorge Juarez-Lucero   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

TLB Coalescing With Range Compressed Page Table for Embedded I/O Devices

open access: yesIEEE Access
Modern embedded system on a chip (SoC) usually accommodates input/output (I/O) memory management units to support virtual memory. When a translation look-aside buffer (TLB) is miss, a page-table walk occurs and frequent page-table walks can significantly
Tran Dai Duong   +2 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Current Situation, Future Trends of Free Economic Zones at the Threshold of the Globalization Era

open access: yesThe Mongolian Journal of International Affairs, 2013
The Mongolian Journal of International Affairs; Number 11, 2004, Page 152-171 DOI: http://dx.doi.org/10.5564/mjia.v0i11 ...
Tsendiin Baatar
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

China and Central Asia: the Role of the Shanghai Cooperation Organization (SCO)

open access: yesThe Mongolian Journal of International Affairs, 2013
The Mongolian Journal of International Affairs; Number 11, 2004, Page 129-151 DOI: http://dx.doi.org/10.5564/mjia.v0i11 ...
Richard Hu
doaj   +1 more source

Home - About - Disclaimer - Privacy