Results 11 to 20 of about 4,842,655 (152)
Protocol for stage 2 of the GaP study (genetic testing acceptability for Paget's disease of bone): A questionnaire study to investigate whether relatives of people with Paget's disease would accept genetic testing and preventive treatment if they were available [PDF]
Background Paget's disease of bone (PDB) disrupts normal bone architecture and causes pain, deformity, deafness, osteoarthritis, and fractures. Genetic factors play a role in PDB and genetic tests are now conducted for research purposes.
McCallum Marilyn +12 more
doaj +3 more sources
Paget's disease of bone may present with bone pain but is often asymptomatic. Treatment (typically with bisphosphonates) is indicated in patients with pain that is localized to an affected site but not in asymptomatic patients.
Ralston, SH
openaire +5 more sources
Paget's disease most commonly affects the breast. Extramammary involvement is rare, and the most commonly affected sites are the vulva, anus, perianal region, and axilla. The disease may progress to invasive adenocarcinoma or synchronous cancers.
Ornella Sari Cassol +5 more
doaj +2 more sources
Paramyxoviruses and Paget's disease.
Using the technique of in situ hybridisation, we extended our initial studies of the occurrence of canine distemper and measles virus in Paget's disease.
Freemont, AJ; id_orcid +4 more
core +10 more sources
Paget’s disease of the vulva is a rare skin cancer accounting for less than 1% of all vulvar neoplasias. Surgery is the first treatment of choice.
Michał Migda +4 more
doaj +1 more source
Tumor-Associated Hypercalcemia in a Patient with Paget's Disease
Paget's disease of the bone, which is characterized by a focal region of highly exaggerated bone remodeling, is very rare in Asia. Most patients with Paget's disease are asymptomatic; they are normocalcemic and show elevated alkaline phosphatase levels ...
Hao-Chang Hung +4 more
doaj +1 more source
The spine in Paget’s disease [PDF]
Paget's disease (PD) is a chronic metabolically active bone disease, characterized by a disturbance in bone modelling and remodelling due to an increase in osteoblastic and osteoclastic activity. The vertebra is the second most commonly affected site. This article reviews the various spinal pathomechanisms and osseous dynamics involved in producing the
Dell’Atti, C. +4 more
openaire +2 more sources
Severe congestive heart failure in elderly patient with Paget’s disease
Paget’s disease of bone is characterized by focal areas of increased bone turnover, affecting one or several bones throughout the skeleton. Paget’s disease is often asymptomatic, but can be associated with bone pain and other skeletal and non-skeletal ...
Lorenzo Palleschi, Eleonora Nunziata
doaj +1 more source
Intraepidermal malignancy in breast skin: A tale of two tumours
Mammary Paget's disease most commonly affects the nipple areolar complex and is frequently associated with an underlying in-situ or invasive breast carcinoma.
Zitong Zhao +5 more
doaj +1 more source
Case of patient with extramammary Paget’s disease
Extramammary Paget’s disease is the infrequently diagnosis in surgical practice, representing a diagnostic challenge. The timely verified diagnosis guarantees successful treatment.
A. Z. Tsitskarava +3 more
doaj +1 more source

