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The spine in Paget’s disease [PDF]
Skeletal Radiology, 2007 Paget's disease (PD) is a chronic metabolically active bone disease, characterized by a disturbance in bone modelling and remodelling due to an increase in osteoblastic and osteoclastic activity. The vertebra is the second most commonly affected site. This article reviews the various spinal pathomechanisms and osseous dynamics involved in producing the
Dell’Atti, C. +4 more
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Journal of Ultrasonography, 2019 Paget’s disease of the vulva is a rare skin cancer accounting for less than 1% of all vulvar neoplasias. Surgery is the first treatment of choice.
Michał Migda +4 more
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Severe congestive heart failure in elderly patient with Paget’s disease
Geriatric Care, 2017 Paget’s disease of bone is characterized by focal areas of increased bone turnover, affecting one or several bones throughout the skeleton. Paget’s disease is often asymptomatic, but can be associated with bone pain and other skeletal and non-skeletal ...
Lorenzo Palleschi, Eleonora Nunziata
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Intraepidermal malignancy in breast skin: A tale of two tumours
Human Pathology: Case Reports, 2018 Mammary Paget's disease most commonly affects the nipple areolar complex and is frequently associated with an underlying in-situ or invasive breast carcinoma.
Zitong Zhao +5 more
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The Journal of Bone and Joint Surgery. British volume, 1979 This chapter focuses on Paget's disease of bone. The pathological hallmark of the Paget's bone disease is excessive and disorganized activity of bone that involves both matrix and mineral. There is no idea of its cause and little knowledge of its natural history; however, the biochemical changes produced by the overactive bone justify its inclusion as ...
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Paget's disease of the breast in a male with lymphomatoid papulosis: a case report
Journal of Medical Case Reports, 2011 Introduction Paget's disease is an eczematous skin change of the nipple that is usually associated with an underlying breast malignancy. Male breast cancer represents only 1-3% of all breast malignancies and Paget's disease remains very rare.
Fouad Dina
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Paget's disease of bone in Tunisia: A study of 69 patients
Indian Journal of Endocrinology and Metabolism, 2020 Context: Paget's disease of bone is a common bone disease with a striking variation in its incidence and characteristics in different parts of the world. It is uncommonly reported in African patients.
Kaouther Maatallah +8 more
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Paget's Disease of the Bone [PDF]
Medical Journal Armed Forces India, 2003 Paget's disease of bone (PDB) is a localised disorder of bone remodelling, characterised by enhanced resorption of bone by giant multinucleated osteoclasis followed by formation of disorganised woven bone by osteoblasts. The resultant bone is expanded, weak and vascular, causing bone pain brittleness and deformity.
K, Narayanan +2 more
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Treatment of Paget’s Disease of Bone
, 2016 Paget's disease involves overactivity of both osteoblasts and osteoclasts within affected bone tissue. It is unclear in which cells the causative lesion resides, but therapies have generally been antiosteoclastic (antiresorptive) because these are the ...
Reid, Ian, Ian R. Reid
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Management of Paget's disease of bone.
, 2020 Paget's disease is a progressive focal bone condition which can result in pain, low quality of life, deformity and other complications. Disease progression can be halted with potent bisphosphonates, resulting in improvement in both quality of life and ...
Reid, Ian
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