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The Journal of Bone and Joint Surgery. British volume, 1979 This chapter focuses on Paget's disease of bone. The pathological hallmark of the Paget's bone disease is excessive and disorganized activity of bone that involves both matrix and mineral. There is no idea of its cause and little knowledge of its natural history; however, the biochemical changes produced by the overactive bone justify its inclusion as ...
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Paget's disease of the breast in a male with lymphomatoid papulosis: a case report
Journal of Medical Case Reports, 2011 Introduction Paget's disease is an eczematous skin change of the nipple that is usually associated with an underlying breast malignancy. Male breast cancer represents only 1-3% of all breast malignancies and Paget's disease remains very rare.
Fouad Dina
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Paget's disease of bone in Tunisia: A study of 69 patients
Indian Journal of Endocrinology and Metabolism, 2020 Context: Paget's disease of bone is a common bone disease with a striking variation in its incidence and characteristics in different parts of the world. It is uncommonly reported in African patients.
Kaouther Maatallah +8 more
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Treatment of Paget’s Disease of Bone
, 2016 Paget's disease involves overactivity of both osteoblasts and osteoclasts within affected bone tissue. It is unclear in which cells the causative lesion resides, but therapies have generally been antiosteoclastic (antiresorptive) because these are the ...
Reid, Ian, Ian R. Reid
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, 2011 Paget's disease is an idiopathic, non-neoplastic affliction characterized by disordered bone formation and resorption. It affects about 3% of the population. Paget's disease affects mainly the skull, femur, tibia and pelvic bones.
GC Rajkumar +3 more
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Journal of Orthopaedic Surgery and Research, 2010 Paget's disease of the bone is a common metabolic bone disease in most European countries, Australia, New Zealand, and North America. Conversely, this disease is rare in Scandinavia, Asia, and Africa.
Fukuta Masashi +4 more
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Extramammary Paget disease [PDF]
Dermatology Online Journal, 2019 In 1874, Sir James Paget first described Paget disease of the nipple, also known as mammary Paget disease. In 1889, extramammary Paget disease (EMPD) of the scrotum and penis was identified. Although mammary and extramammary Paget disease are both characterized by epidermal Paget cells and share a similar clinical presentation, their uniqueness lies in
St. Claire, Kayla +3 more
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Cell biology of Paget's disease
, 1999 Paget's disease is characterized by markedly increased osteoclast formation and bone resorption followed by excessive new bone formation. Osteoclasts in Paget's disease are increased both in number and size, contain paramyxoviral-like nuclear inclusions,
Reddy, Sakamuri S.V. +9 more
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Management of Paget's disease of bone.
, 2020 Paget's disease is a progressive focal bone condition which can result in pain, low quality of life, deformity and other complications. Disease progression can be halted with potent bisphosphonates, resulting in improvement in both quality of life and ...
Reid, Ian
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Articular complications of Paget's disease of bone
, 1994 Articular symptoms in Paget's disease are very common. The most frequent cause of articular symptoms is OA, secondary to the Paget's disease. Radiographie OA due to Paget's disease is not always symptomatic, and periarticular Paget's disease does not ...
Altman, Roy D
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