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Diagnosis and treatment of Paget's disease of bone: position paper from the Italian Society of Osteoporosis, Mineral Metabolism and Skeletal Diseases (SIOMMMS). [PDF]
J Endocrinol InvestRendina D +17 more
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Diagnosis and Management of Paget's Disease of Bone in Adults: A Clinical Guideline. [PDF]
J Bone Miner Res, 2019 Ralston SH +16 more
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Calcified Tissue International, 2019
Paget's disease of bone (PDB) is a chronic and focal bone disorder, characterized by increased osteoclast-mediated bone resorption and a subsequent compensatory increase in bone formation, resulting in a disorganized mosaic of woven and lamellar bone at one or more affected skeletal sites.
Luigi Gennari +3 more
openaire +5 more sources
Paget's disease of bone (PDB) is a chronic and focal bone disorder, characterized by increased osteoclast-mediated bone resorption and a subsequent compensatory increase in bone formation, resulting in a disorganized mosaic of woven and lamellar bone at one or more affected skeletal sites.
Luigi Gennari +3 more
openaire +5 more sources
Trends in Endocrinology & Metabolism, 2008
Despite significant advances in management, Paget disease remains an enigmatic disorder. There are no animal models, and while its end result --a focal disorder of accelerated bone turnover--is easily recognized, the causes and evolution of the disorder remain uncertain.
Tim, Cundy, Mark, Bolland
openaire +4 more sources
Despite significant advances in management, Paget disease remains an enigmatic disorder. There are no animal models, and while its end result --a focal disorder of accelerated bone turnover--is easily recognized, the causes and evolution of the disorder remain uncertain.
Tim, Cundy, Mark, Bolland
openaire +4 more sources
Seminars in Musculoskeletal Radiology, 2002
Paget's disease of bone is one of the most common diseases to affect bone, yet it is rare before the age of 50. The etiology of the condition remains unproven. Paget's disease of bone has become less common, less severe, and less extensive in recent decades.
Frederick R. Singer, G. David Roodman
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Paget's disease of bone is one of the most common diseases to affect bone, yet it is rare before the age of 50. The etiology of the condition remains unproven. Paget's disease of bone has become less common, less severe, and less extensive in recent decades.
Frederick R. Singer, G. David Roodman
openaire +3 more sources
Orthopedic Clinics of North America, 1990
Paget's disease of bone is defined as a process of increased bone remodeling; the primary event is increased resorption (osteoclastic activity) followed by subsequent reactive bone formation (osteoblastic activity). It is usually asymmetric and may be asymptomatic.
R L, Merkow, J M, Lane
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Paget's disease of bone is defined as a process of increased bone remodeling; the primary event is increased resorption (osteoclastic activity) followed by subsequent reactive bone formation (osteoblastic activity). It is usually asymmetric and may be asymptomatic.
R L, Merkow, J M, Lane
openaire +3 more sources
Best Practice & Research Clinical Rheumatology, 2003
Paget's disease of bone is characterized by an anarchic bone remodelling, associated with morphological and functional abnormalities of osteoclasts. Its prevalence and incidence rates decreased gradually over the past two decades; the reason for this remains unclear.
Mickaël, Rousière +3 more
openaire +2 more sources
Paget's disease of bone is characterized by an anarchic bone remodelling, associated with morphological and functional abnormalities of osteoclasts. Its prevalence and incidence rates decreased gradually over the past two decades; the reason for this remains unclear.
Mickaël, Rousière +3 more
openaire +2 more sources