Results 171 to 180 of about 166,331,801 (189)
Some of the next articles are maybe not open access.
Orthopedic Clinics of North America, 1990
Paget's disease of bone is defined as a process of increased bone remodeling; the primary event is increased resorption (osteoclastic activity) followed by subsequent reactive bone formation (osteoblastic activity). It is usually asymmetric and may be asymptomatic.
R L, Merkow, J M, Lane
openaire +3 more sources
Paget's disease of bone is defined as a process of increased bone remodeling; the primary event is increased resorption (osteoclastic activity) followed by subsequent reactive bone formation (osteoblastic activity). It is usually asymmetric and may be asymptomatic.
R L, Merkow, J M, Lane
openaire +3 more sources
Orthopedic Clinics of North America, 2015
The current understanding of Paget disease of bone (PDB) has vastly changed since Paget described the first case in 1877. Medical management of this condition remains the mainstay of treatment. Surgical intervention is usually only used in fractures through pagetic bone, need for realignment to correct deformity in major long bones, prophylactic ...
Mamun, Al-Rashid +5 more
openaire +2 more sources
The current understanding of Paget disease of bone (PDB) has vastly changed since Paget described the first case in 1877. Medical management of this condition remains the mainstay of treatment. Surgical intervention is usually only used in fractures through pagetic bone, need for realignment to correct deformity in major long bones, prophylactic ...
Mamun, Al-Rashid +5 more
openaire +2 more sources
Trends in Endocrinology & Metabolism, 1991
Paget's disease of bone is a common disorder of older patients that may sometimes cause a variety of signs and symptoms referable to the skeleton. An intrinsic bone-remodeling abnormality in this disease may lead to bone deformity, pain, and various arthritic or neurologic complications.
E S, Siris, R E, Canfield
openaire +2 more sources
Paget's disease of bone is a common disorder of older patients that may sometimes cause a variety of signs and symptoms referable to the skeleton. An intrinsic bone-remodeling abnormality in this disease may lead to bone deformity, pain, and various arthritic or neurologic complications.
E S, Siris, R E, Canfield
openaire +2 more sources
Trends in Endocrinology & Metabolism, 2008
Despite significant advances in management, Paget disease remains an enigmatic disorder. There are no animal models, and while its end result --a focal disorder of accelerated bone turnover--is easily recognized, the causes and evolution of the disorder remain uncertain.
Tim, Cundy, Mark, Bolland
openaire +2 more sources
Despite significant advances in management, Paget disease remains an enigmatic disorder. There are no animal models, and while its end result --a focal disorder of accelerated bone turnover--is easily recognized, the causes and evolution of the disorder remain uncertain.
Tim, Cundy, Mark, Bolland
openaire +2 more sources
Current Opinion in Endocrinology, Diabetes & Obesity, 2011
Abstract In 1876, Sir James Paget presented to the Royal Medical and Chirurgical Society of London an account of his experience with a previously unrecognized disease of the skeleton, which he termed osteitis deformans and has since born his name.
openaire +3 more sources
Abstract In 1876, Sir James Paget presented to the Royal Medical and Chirurgical Society of London an account of his experience with a previously unrecognized disease of the skeleton, which he termed osteitis deformans and has since born his name.
openaire +3 more sources
Best Practice & Research Clinical Rheumatology, 2003
Paget's disease of bone is characterized by an anarchic bone remodelling, associated with morphological and functional abnormalities of osteoclasts. Its prevalence and incidence rates decreased gradually over the past two decades; the reason for this remains unclear.
Mickaël, Rousière +3 more
openaire +2 more sources
Paget's disease of bone is characterized by an anarchic bone remodelling, associated with morphological and functional abnormalities of osteoclasts. Its prevalence and incidence rates decreased gradually over the past two decades; the reason for this remains unclear.
Mickaël, Rousière +3 more
openaire +2 more sources
Clinical Biochemistry, 2012
To review recent advance in understanding the causation and management of Paget's disease.We review recent publications concerning the aetiology of the disease and the use of biochemical markers of bone turnover in diagnosis and treatment.Epidemiologic studies suggest that Paget's disease is decreasing in prevalence and severity (implying that ...
Tim, Cundy, Ian R, Reid
openaire +2 more sources
To review recent advance in understanding the causation and management of Paget's disease.We review recent publications concerning the aetiology of the disease and the use of biochemical markers of bone turnover in diagnosis and treatment.Epidemiologic studies suggest that Paget's disease is decreasing in prevalence and severity (implying that ...
Tim, Cundy, Ian R, Reid
openaire +2 more sources
Medical Journal of Australia, 2004
Paget's disease of bone is common, affecting up to 4% of Australians over the age of 55 years. The incidence of the disease and the severity of newly diagnosed cases appear to be falling, for unknown reasons. The cause of Paget's disease is unknown, but there is a strong genetic influence.
openaire +2 more sources
Paget's disease of bone is common, affecting up to 4% of Australians over the age of 55 years. The incidence of the disease and the severity of newly diagnosed cases appear to be falling, for unknown reasons. The cause of Paget's disease is unknown, but there is a strong genetic influence.
openaire +2 more sources
Seminars in Musculoskeletal Radiology, 2016
Paget disease (PD) is a common disease of bone associated with abnormal bone turnover that in turn is due to an imbalance between osteoclastic and osteoblastic activity. There is good evidence that PD is reducing in incidence, prevalence, and severity.
Radhesh Krishna, Lalam +2 more
openaire +2 more sources
Paget disease (PD) is a common disease of bone associated with abnormal bone turnover that in turn is due to an imbalance between osteoclastic and osteoblastic activity. There is good evidence that PD is reducing in incidence, prevalence, and severity.
Radhesh Krishna, Lalam +2 more
openaire +2 more sources
The British Journal of Radiology, 1954
When I was invited by Professor Trueta to give a lecture I chose this subject because it is a condition which is recognisable by radiography long before the clinical evidence is distinctive and because I am able to demonstrate these earlier radiographic signs; though if you ask me what value I confer on the community by this early recognition I am less
openaire +2 more sources
When I was invited by Professor Trueta to give a lecture I chose this subject because it is a condition which is recognisable by radiography long before the clinical evidence is distinctive and because I am able to demonstrate these earlier radiographic signs; though if you ask me what value I confer on the community by this early recognition I am less
openaire +2 more sources