Results 61 to 70 of about 1,270 (206)

Perianal Paget's Disease: A Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Perianal Paget's disease is rare and may be secondary to an underlying anorectal adenocarcinoma. Full‐thickness biopsy with immunohistochemistry is key to distinguish primary from secondary disease and to guide staging. Wide local excision is standard, while radiotherapy is a reasonable option when radical surgery is declined.
Daniela Lira, Maria Reigota Miranda, Marta Serra, Margarida Martins, Júlio Alves, Joana Noronha   +5 more
wiley   +1 more source

The Msi1-mTOR pathway drives the pathogenesis of mammary and extramammary Paget’s disease [PDF]

, 2020
Mammary and extramammary Paget's Diseases (PD) are a malignant skin cancer characterized by the appearance of Paget cells. Although easily diagnosed, its pathogenesis remains unknown.
Bi, Xueyun, Ma, Xianghui, Dai, Xing, Nie, Qing, Guerrero-Juarez, Christian F, Plikus, Maksim V, Ying, Zhaoxia, Xu, Jiuzhi, Andersen, Bogi, Zhu, Yunlu, Lv, Cong, Deng, Min, Song, Yongli, Du, Sujuan, Shuai, Jianwei, Chen, Zhongjian, Ren, Fazheng, Chen, Hong-duo, Yu, Zhengquan, Tang, Yichen, Tian, Yuhua, Liu, Ruiqi, Zhao, Ran, Sheng, Xiaole, Zhao, Yiqiang, Lengner, Christopher J, Zhou, Guangbiao, Shan, Shi-jun, Bu, Lina, Liu, Yeqiang, Xue, Lixiang   +30 more
core   +1 more source

Cutaneous Apocrine Adenocarcinoma of the Groin With Extramammary Paget Disease: Response to Dual HER2 Blockade With Trastuzumab and Pertuzumab [PDF]

, 2022
Adenocarcinoma apocrino cutáneo; Enfermedad de Paget extramamaria; TratamientoAdenocarcinoma apocri cutani; Malaltia de Paget extramamària; TractamentCutaneous apocrine adenocarcinoma; Extramammary Paget's disease; TreatmentEl carcinoma apocrino cutáneo ...
Sola-Ortigosa, Joaquin, Muñoz Santos, Carlos, Hernández-Bronchud, Miguel, Guilabert, Antonio   +3 more
core   +1 more source

Paget’s disease derived in situ from reserve cell hyperplasia, squamous metaplasia, and squamous cell carcinoma of the esophagogastric junction: a case report

Surgical Case Reports, 2018
Background Extramammary Paget’s disease (EMPD) of the esophagus is a rare tumor, with most cases originating from invasive adenocarcinoma of the esophagus.
Akihiko Sano, Shinji Sakurai, Chika Komine, Yuichi Tabe, Kana Saito, Takaharu Fukasawa, Shinsuke Kiriyama, Hideki Yamamoto, Masachika Tani, Hiroshi Naitoh, Ken Shirabe, Hiroyuki Kuwano   +11 more
doaj   +1 more source

Dermatologic Features of Endocrine Tumor Syndromes—Systematic Review and Meta‐Analysis

International Journal of Dermatology, Volume 65, Issue 3, Page 464-488, March 2026.
ABSTRACT Endocrine tumor syndromes, including multiple endocrine neoplasia types 1, 2A, and 2B (MEN1, MEN2A, MEN2B), Carney complex (CNC), and PTEN hamartoma tumor syndrome (PHTS), are hereditary conditions characterized by multisystem tumor development.
Sára Pálla, Zseraldin Metyovinyi, Fanni Adél Meznerics, Arash Mirzahosseini, Judit Tőke, Miklós Tóth, Henriett Butz, Attila Patócs, Márta Medvecz   +8 more
wiley   +1 more source

Ectopic Extramammary Paget`s Disease of the Breast Skin: A Case Report

, 2010
Whereas extramammary Paget`s disease commonly occurs in the apocrine gland rich skin areas, ectopic extramammary Paget`s disease develops in the skin areas that are devoid of apocrine glands.
노동영, 정인목, 장미수, 안혜성, 허승철, 안영준, 정중기, 김혜영, 이종희, 황기태   +9 more
core   +1 more source

Extramammary Paget’s disease of the scrotum

Journal of the Chinese Medical Association, 2011
Extramammary Paget's disease is an uncommon intra-epidermal malignant neoplasm that arises in area rich in apocrine glands. Common sites of occurrence include the vulva, perianal region, perineum, and scrotum. The lesion may be accompanied by an invasive adenocarcinoma or adenocarcinoma in situ of the apocrine glands.
Juang, Guang-Dar, Lin, Meng-Yan, Hwang, Thomas I-Sheng   +2 more
openaire   +2 more sources

Scrotal squamous cell carcinoma: Two HPV‐negative cases with probable UV‐ induced pathogenesis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Daniel Craus, Ulrike Wieland, Steffi Silling, Julia Hyun, Milan Vidakovic, Frank Oellig, Alexander Kreuter, Valentina Laura Müller   +7 more
wiley   +1 more source

Glucocorticoid Receptor Activation Reprograms NK Cells to Drive AREG‐Mediated Immunosuppression: A Pan‐Cancer Role for AREG

Advanced Science, Volume 13, Issue 2, 9 January 2026.
Natural killer cells, central to anti‐tumor defense, undergo unexpected reprogramming within the tumor microenvironment. Instead of producing IFN‐γ and TNF‐α, they elevate amphiregulin, a tumor‐promoting factor. This shift is linked to glucocorticoid receptor activity and prostaglandin signaling.
Qin Wei, Guirong Liang, Rui zeng, Yuancheng Li, Anlan Hong, Hongsheng Wang, Suying Feng, Yan Wang, Yetao Wang   +8 more
wiley   +1 more source

Correspondence: Primary Cutaneous NUT Adnexal Carcinoma: A Case Report With Novel Clinical and Pathological Observations

Journal of Cutaneous Pathology, Volume 53, Issue 7, Page 622-623, July 2026.
Woo Cheal Cho
wiley   +1 more source