Results 71 to 80 of about 4,852,169 (202)

Glucocorticoid Receptor Activation Reprograms NK Cells to Drive AREG‐Mediated Immunosuppression: A Pan‐Cancer Role for AREG

open access: yesAdvanced Science, Volume 13, Issue 2, 9 January 2026.
Natural killer cells, central to anti‐tumor defense, undergo unexpected reprogramming within the tumor microenvironment. Instead of producing IFN‐γ and TNF‐α, they elevate amphiregulin, a tumor‐promoting factor. This shift is linked to glucocorticoid receptor activity and prostaglandin signaling.
Qin Wei   +8 more
wiley   +1 more source

Avaliação clínico laboratorial e imunogenética de pacientes com doença óssea de Paget [PDF]

open access: yes, 2014
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Ciências Médicas, Florianópolis, 2014.Introdução: Muitos aspectos da etiopatogênese da doença óssea de Paget ainda estão por ser ...
Castro, Gláucio Ricardo Werner de
core  

Extramammary pagets disease of scrotum: A case with local lymph node metastasis [PDF]

open access: yes, 2005
OBJETIVE: We describe the clinical, histological and immunohistochemical studies in a case of extramammary Paget´s disease localized in the scrotum with lymph node inguinal metastasis.
Parada,David   +5 more
core   +1 more source

Invasive acantholytic anaplastic extramammary Paget disease: A previously unreported neoplasm in the vulva and review of the literature

open access: yesGynecologic Oncology Reports
This report describes the first documented invasive acantholytic anaplastic extramammary Paget disease (AAEMPD) of the vulva. An 87-year-old female presented with a recurrent vulvar lesion refractory to topical imiquimod and treated with multiple wide ...
Flora Mae G. Sta. Ines   +4 more
doaj   +1 more source

Single‐Center Epidemiological Analysis of Malignant Transformation With Skin Ulcers in Outpatients

open access: yesInternational Wound Journal, Volume 23, Issue 1, January 2026.
ABSTRACT Investigate the epidemiological characteristics of outpatients initially diagnosed with skin ulcers who were ultimately confirmed to have cutaneous malignant tumours, and provide a diagnostic and therapeutic basis for the occurrence of secondary diseases in chronic wounds.
Yaoyao Kong   +11 more
wiley   +1 more source

Ectopic Extramammary Paget`s Disease of the Breast Skin: A Case Report

open access: yes, 2010
Whereas extramammary Paget`s disease commonly occurs in the apocrine gland rich skin areas, ectopic extramammary Paget`s disease develops in the skin areas that are devoid of apocrine glands.
노동영   +9 more
core   +1 more source

Multifocal extramammary Paget’s disease-associated adenocarcinoma: a rare condition of flexoral skin of multiple sites [PDF]

open access: yes, 2016
Extramammary Paget disease (EMPD) is a rare malignant neoplasm of apocrine sweat glands that is morphologically and histologically identical to Paget disease of the breast.
Rapini, Ronald   +3 more
core   +1 more source

Recurrent extramammary Paget’s disease successfully treated with peripheric Mohs micrographic surgery associated with rapid immunohistochemistry [PDF]

open access: yesSurgical & Cosmetic Dermatology
Extramammary Paget's disease is a slow-progressing, cutaneous adenocarcinoma of the apocrine glands with an uncertain etiology. The standard treatment is surgical removal of the tumor.
José Antonio Jabur   +3 more
doaj   +1 more source

Epidermotropic Metastatic Prostate Adenocarcinoma With Florid Squamous Transformation/Differentiation and Associated Acantholysis. An Unusual Clinicopathologic Entity

open access: yesCase Reports in Dermatological Medicine, Volume 2026, Issue 1, 2026.
Prostate adenocarcinoma is the most common carcinoma in men. Cutaneous metastasis of prostate adenocarcinoma, however, is rare, accounting for less than 1% of metastatic cutaneous carcinomas. This cutaneous spread most often occurs in the inguinal area and the penis, followed by the abdomen, head and neck, chest, extremities, and back.
Sara J. Hoffman   +3 more
wiley   +1 more source

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