Results 71 to 80 of about 1,270 (206)

Single‐Center Epidemiological Analysis of Malignant Transformation With Skin Ulcers in Outpatients

International Wound Journal, Volume 23, Issue 1, January 2026.
ABSTRACT Investigate the epidemiological characteristics of outpatients initially diagnosed with skin ulcers who were ultimately confirmed to have cutaneous malignant tumours, and provide a diagnostic and therapeutic basis for the occurrence of secondary diseases in chronic wounds.
Yaoyao Kong, Haixia Wang, Nan Cao, Pengcheng Huai, Zhenzhen Wang, Chaoqi Zuo, Xueqing Wang, Yilei Wu, Yongxia Liu, Shengli Chen, Hong Liu, Guangliang Zhang   +11 more
wiley   +1 more source

Metastatic extramammary paget disease, a remarkable clinical case and a brief review of a rare disease

Dermatology Reports, 2020
Extramammary Paget Disease (EMPD) is an often-misdiagnosed rare disorder, whose cause remains unknown. Diagnosis is confirmed by skin biopsy. Primary treatment for EMPD is surgery.
Leonor Fernandes, Joana Graça, Leonor Vasconcelos de Matos, Rita Sampaio, Mafalda Miranda Baleiras, Filipa Ferreira, Marta Mesquita Pinto, Helena Miranda, Ana Martins   +8 more
doaj   +1 more source

The Roles of MicroRNAs, Oncogenes, and Tumor Suppressor Gene Molecular Subtypes of Breast Cancer: Therapeutic Potential of Pharmaceutical and Natural Products

International Journal of Breast Cancer, Volume 2026, Issue 1, 2026.
Background Breast cancer (BC) is the most common malignancy among women, with 2.3 million new cases and over 670,000 deaths annually. Despite advances in detection and therapy, relapse, metastasis, and resistance remain significant challenges. Tumor suppressor genes (TSGs) regulate abnormal cell division, whereas oncogenes, which arise from proto ...
Md. Sadikuj Jaman, Md. Maniruzzaman, Md. Rokibul Hasan Bhuiyan, Md Shajedul Haque, Irfan Ahmad   +4 more
wiley   +1 more source

First Case of Primary Breast Melanoma in Central America: Case Report and Literature Review

Clinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT Primary breast melanoma is an exceedingly rare neoplasm, accounting for < 0.5% of all malignant breast tumors. Its scarcity and highly variable clinical presentation often delay diagnosis and complicate management. We report the case of a 55‐year‐old woman with a primary non‐cutaneous melanoma of the right breast initially misdiagnosed as high‐
Ana García‐Urbina, Denis Espinoza‐Vásquez, Johanna Obregón‐Silva, Arlin Montoya Rodríguez   +3 more
wiley   +1 more source

Mohs micrographic surgical approach in a case of extramammary Paget&amp;apos;s disease

, 2020
A 67-year-old man noted a 4x6cm sized, erythematous, erosive, oozing patch on the penile shaft, which resisted conservative therapy for three years.
황규광
core  

Extramammary Paget disease of the perianal region:the potential role of imiquimod in achieving disease control [PDF]

, 2016
Extramammary Paget disease (EMPD) is a rare perineal neoplasia associated with a high rate of local recurrence. Surgical excision is the standard treatment; however, this has high rates of post-operative morbidity in combination with potentially ...
Knight, Stephen R., Carey, Frank, Ziyaie, Dorin, Koch, Sacha, Proby, Charlotte   +4 more
core   +1 more source

Japanese Dermatological Association Guidelines: Clinical Questions of Guidelines for Merkel Cell Carcinoma 2025

The Journal of Dermatology, Volume 52, Issue 11, Page e954-e967, November 2025.
ABSTRACT Merkel cell carcinoma (MCC) is a highly malignant skin cancer characterized by high rates of recurrence and metastasis. Although rare, the incidence has noticeably increased in recent years. It is also known to be a highly immunogenic tumor, and the use of immune checkpoint inhibitors has begun for advanced cases.
Motoki Nakamura, Kotaro Nagase, Junji Kato, Masahito Yasuda, Natsuo Tomita, Tadahiro Kobayashi, Keitaro Fukuda, Akihiko Yuki, Hiroshi Uchi, Hiroshi Koga, Tomomitsu Miyagaki, Yasuhiro Nakamura   +11 more
wiley   +1 more source

Extramammary Paget Disease: Review of Patients Seen in a Non-Melanoma Skin Cancer Clinic

, 2010
Extramammary Paget disease (EMPD) is a rare skin disease commonly found in the anogenital region. In this study, we aimed to identify EMPD patients seen in the non-melanoma skin cancer clinic at Odette Cancer Centre and to describe the treatments ...
O. Antonyshyn, J. Balogh, J. Pang, E.A. Barnes, M. Tsao, J. Kamra, D. Assaad, D. Breen, G. Czarnota, J. Fialkov   +9 more
core   +1 more source

Invasive acantholytic anaplastic extramammary Paget disease: A previously unreported neoplasm in the vulva and review of the literature

Gynecologic Oncology Reports
This report describes the first documented invasive acantholytic anaplastic extramammary Paget disease (AAEMPD) of the vulva. An 87-year-old female presented with a recurrent vulvar lesion refractory to topical imiquimod and treated with multiple wide ...
Flora Mae G. Sta. Ines, Julia R. Salinaro, Mary Marchese, Cara A. Mathews, M. Ruhul Quddus   +4 more
doaj   +1 more source

An Evaluation of HER2 Expression Heterogeneity in Primary Tumors and Metastatic Lymph Nodes of Patients With Advanced Extramammary Paget's Disease: Prognostic and Therapeutic Implications

Cancer Medicine, Volume 14, Issue 19, October 2025.
ABSTRACT Background HER2 expression in primary versus metastatic tumors in advanced Extramammary Paget's Disease (EMPD) remains inadequately characterized. This investigation aimed to assess HER2 expression heterogeneity between primary tumors and metastatic lymph nodes (LNs) in patients with advanced EMPD and to assess the prognostic value of HER2 ...
Zhicheng Liu, Xingliang Tan, Zhiming Wu, Yi Tang, Qianghua Zhou, Wensu Wei, Cong Yang, Long Huang, Yanjun Wang, Kai Yao   +9 more
wiley   +1 more source