Results 81 to 90 of about 4,852,169 (202)

Treatment of Extramammary Paget Disease and the Role of Reflectance Confocal Microscopy: A Prospective Study

, 2021
BACKGROUND Extramammary Paget disease (EMPD) poses treatment challenges. Invasive and noninvasive treatment modalities exist with variable success reported. Reflectance confocal microscopy (RCM) is emerging as an adjuvant diagnostic tool.
Melissa Pulitzer, Travis Hollmann, Andrea Moy, Navarrete-Dechent, Cristian, Leitao, Mario M., Jr., Busam, Klaus J., Erlendsson, Andres M., Anthony M. Rossi, Aleissa, Saud, Andres M. Erlendsson, Klaus J. Busam, Lezcano, Cecilia, Miguel Cordova, Cordova, Frank, Cristian Navarrete-Dechent, Cecilia Lezcano, Lee, Erica H., Erica H. Lee, Hollmann, Travis, Pulitzer, Melissa, Brian P. Hibler, Frank Cordova, Mario M. Leitao, Rossi, Anthony M., Polansky, Max, Max Polansky, Saud Aleissa, Hibler, Brian P., Cordova, Miguel, Moy, Andrea   +29 more
core   +1 more source

The Roles of MicroRNAs, Oncogenes, and Tumor Suppressor Gene Molecular Subtypes of Breast Cancer: Therapeutic Potential of Pharmaceutical and Natural Products

International Journal of Breast Cancer, Volume 2026, Issue 1, 2026.
Background Breast cancer (BC) is the most common malignancy among women, with 2.3 million new cases and over 670,000 deaths annually. Despite advances in detection and therapy, relapse, metastasis, and resistance remain significant challenges. Tumor suppressor genes (TSGs) regulate abnormal cell division, whereas oncogenes, which arise from proto ...
Md. Sadikuj Jaman, Md. Maniruzzaman, Md. Rokibul Hasan Bhuiyan, Md Shajedul Haque, Irfan Ahmad   +4 more
wiley   +1 more source

Enfermedad de Paget extramamaria de la ingle tratada con imiquimod tópico al 5 % [PDF]

, 2019
Paget\u27s disease is an intraepithelial adenocarcinoma, which appears on the nipple-areola complex or, in its extramammary form, on anatomical regions rich in apocrine glands.
Ruiz, Astrid Lorena, Morales, Camilo Andrés   +1 more
core  

Primary vulvar Paget disease – the importance of clinical suspicion [PDF]

, 2017
Extramammary Paget disease of the vulva is a rare condition that accounts for only 1-2% of vulvar malignancies and represents a frequent cause of misdiagnosis. It is most commonly seen in postmenopausal women. Clinically it is similar to Paget disease of
Mota, Fernando, Marques, Claudia, Selores, Manuela, Horta, Miguel, Foreid, Susan   +4 more
core   +3 more sources

Repair of Scrotal Wounds after Extensive Excision of Extramammary Paget Disease with Thick Split-thickness Skin Graft

Plastic and Reconstructive Surgery, Global Open
Summary:. Extramammary Paget disease (EMPD) is a rare cutaneous malignant tumor. Currently, surgery is the most recommended treatment for EMPD. Here, we present a case of EMPD involving the groin, penis, and scrotum.
Yi Chen, Ke-Rong Tao, MM, Zhao-He Luo, MM, Guang-Feng Sun, MM   +3 more
doaj   +1 more source

Perianal Pagetoid Intraepithelial Carcinoma

Case Reports in Gastroenterology, 2017
Extramammary Paget disease (EMPD) involving the perianal region is rare and challenging to manage. Primary EMPD involves stand-alone noninvasive lesions within the epidermis, while secondary EMPD involves phenotypically similar lesions derived from ...
Suanga Sisodia, Robin Boushey, Goo Lee, Celia Marginean, Marcio M. Gomes, Gaurav Bhattacharya, Kristopher Dennis   +6 more
doaj   +1 more source

Vulvar Adenocarcinoma With Pagetoid Spread: A Case Report

Cancer Reports
Background In rare cases, cancer cells adjacent to the skin migrate intraepithelially and reach the epidermis, presenting a histological appearance similar to that of Paget's disease; this phenomenon is termed pagetoid spread. Herein, we report a case of
Kazuaki Nishimura, Seiji Kagami, Haruka Kajio, Tamaki Wada, Naoyuki Toki, Kiyoshi Yoshino   +5 more
doaj   +1 more source

An Asymptomatic Lesion on the Penis

JEADV Clinical Practice, Volume 5, Issue 1, Page 309-311, March 2026.
Brandon Tan, Karen Cheung, Xin Liu, Alexis Daniel Lara Rivero   +3 more
wiley   +1 more source

Case report: Pyrotinib in the treatment of advanced scrotal EMPD combined with sweat gland carcinoma

Frontiers in Oncology
Extramammary Paget disease (EMPD) is a rare cutaneous intraepithelial adenocarcinoma, which is mostly distributed in areas with sweat gland cells and mainly occurs in the anogenital skin of women.
Liquan Zhu, Liquan Zhu, Haoqiang Wang, Donghai Cheng, Wei Wang, Yue Lei, Yue Lei, Ning Yang, Lijun Peng, Peng Liu, Juan Zhou, Bo Xie   +11 more
doaj   +1 more source

Extramammary Paget Disease: Review of Patients Seen in a Non-Melanoma Skin Cancer Clinic

, 2010
Extramammary Paget disease (EMPD) is a rare skin disease commonly found in the anogenital region. In this study, we aimed to identify EMPD patients seen in the non-melanoma skin cancer clinic at Odette Cancer Centre and to describe the treatments ...
O. Antonyshyn, J. Balogh, J. Pang, E.A. Barnes, M. Tsao, J. Kamra, D. Assaad, D. Breen, G. Czarnota, J. Fialkov   +9 more
core   +1 more source