Results 81 to 90 of about 1,691 (205)

The evolving role of TRPS1 in dermatopathology: insights from the past 4 years [PDF]

Journal of Pathology and Translational Medicine
Over the past 4 years, trichorhinophalangeal syndrome type 1 (TRPS1) has rapidly gained attention among practicing pathologists, with numerous studies emerging that both support and question its diagnostic utility. Initially regarded as a highly specific
Mokhtar H. Abdelhammed, Woo Cheal Cho
doaj   +1 more source

CXCL13 and CCL21 Induce Tertiary Lymphoid Structures and Enhance the Efficacy of Immunotherapy for Melanoma

Cancer Science, Volume 116, Issue 8, Page 2075-2085, August 2025.
Plasma CCL21 levels were significantly increased in tertiary lymphoid structures (TLS)‐positive melanoma cases both before and after immune checkpoint inhibitors (ICI) treatment, while CXCL13 levels were significantly elevated after ICI treatment. We successfully induced TLS by co‐administering CXCL13 and CCL21 in a mouse melanoma model, clarifying ...
Maki Yoshimitsu, Motoki Nakamura, Shinji Kano, Tetsuya Magara, Hiroshi Kato, Aiko Sakai, Masaya Sugiyama, Masashi Mizokami, Akimichi Morita   +8 more
wiley   +1 more source

Patología no infecciosa de la vulva.Revisión de la literatura y puesta al día. [PDF]

, 2017
La vulva es el conjunto de los órganos genitales externos de la mujer y comprende el área topográfica delimitada por el monte de Venus anteriormente, el periné en su parte posterior, los pliegues inguinales a ambos lados y el anillo himeneal medialmente.
González Santana, Cintia
core  

Neoadjuvant use of Imiquimod Before Surgery in Extramammary Paget’s Disease [PDF]

, 2018
A doença de Paget extramamária (DPEM) é uma neoplasia maligna cutânea, rara, observada principalmente em mulheres caucasianas pós-menopausa. A cirurgia é o tratamento mais comum.
Azevedo, F., Costa e Silva, M., Costa, J. S., Costa, M. A., Lisboa, Carmen   +4 more
core   +2 more sources

Longstanding Perianal Ulcers

JEADV Clinical Practice, Volume 4, Issue 5, Page 1274-1277, December 2025.
Narachai Julanon, Thanaphon Anutraungkool, Sirawich Jessadapattarakul, Vincent Piguet   +3 more
wiley   +1 more source

Enhancing inguinal tumor treatment outcomes with a customized 3D‐printed bolus

Journal of Applied Clinical Medical Physics, Volume 26, Issue 7, July 2025.
Abstract Traditional boluses for pelvic lesions present challenges, including compromised skin dose coverage from large air gaps in treatment plans and increased uncertainties in treatment delivery due to variations in bolus fitting. This study evaluates the clinical benefits of a patient‐specific, 3D‐printed bolus (pBolus) in external beam radiation ...
Xing Li, Stephen Bhagroo, Fan‐Chi Su, Robabeh Rahimi, Jonathan Tward   +4 more
wiley   +1 more source

A Case of Concurrent Extramammary Paget Disease and Basal Cell Carcinoma of the Perianal Region

Plastic and Reconstructive Surgery, Global Open, 2020
Summary:. An 83-year-old Japanese man who had been aware of a tumor near his anus for 2 years underwent tumor resection. Although he was diagnosed with basal cell carcinoma (BCC), extramammary Paget disease (EMPD) was also accidentally found in the same ...
Natsuko Takahashi, MD, Yoshiyuki Okumura, MD, Eiichi Sawaragi, MD   +2 more
doaj   +1 more source

Atypisch junctioneel melanocytoma met pagetoïde spreiding bij een jong paard [PDF]

, 2018
Melanocytic tumors are commonly encountered neoplasms in horses. In this case report, an atypical case of a melanocytoma in an almost five-year-old Andalusian horse is described.
Ducatelle, Richard, Haspeslagh, Maarten, Sonck, Laurien   +2 more
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Predictors of Dermal Invasion and Sentinel Lymph Node Metastasis in Patients With Extramammary Paget's Disease Without Clinical Lymph Node Enlargement

The Journal of Dermatology, Volume 52, Issue 7, Page 1152-1158, July 2025.
ABSTRACT Sentinel lymph node biopsy (SLNB) has prognostic value in extramammary Paget's disease (EMPD) without lymph node enlargement; however, its therapeutic value is unknown. The likelihood of sentinel lymph node metastasis is extremely low, especially when the primary tumor is an intraepidermal lesion; therefore, sentinel node biopsy should not be ...
Ken Horisaki, Shusuke Yoshikawa, Wataru Omata, Arata Tsutsumida, Yoshio Kiyohara   +4 more
wiley   +1 more source

Surgical Treatment of Paget Disease of the Vulva [PDF]

, 2016
ObjectiveThe aim of the study was to evaluate the risk of recurrence according to the surgical margin status and the presence of invasion or of superficially invasive carcinoma in patients with extramammary Paget disease (EMPD) of the vulva, who ...
Buttignol, Monica, Canzonieri, Vincenzo, Ciavattini, Andrea, De Piero, Giovanni, Di Giuseppe, Jacopo, Giorda, Giorgio, Sopracordevole, Francesco   +6 more
core   +1 more source