Results 211 to 220 of about 205,885 (332)

The relationship between the cannabinoids and cardiac remodelling: A comprehensive review of pivotal mechanisms and emerging evidence

British Journal of Pharmacology, EarlyView.
Cardiac remodelling and fibrosis after myocardial infarction or during chronic diseases, such as arterial and pulmonary hypertension or diabetes mellitus, continue to be the more important prognostic factors in determining survival, and so the search for effective anti‐fibrotic interventions is an important target for research and therapy in cardiology.
Anna Krzyżewska, Marta Baranowska‐Kuczko, Hanna Kozłowska   +2 more
wiley   +1 more source

<i>L</i>-region-selective annulative π-extension through dearomative activation of polycyclic aromatic hydrocarbons. [PDF]

Chem Sci
Nakata K, Matsuoka W, Ito H, Itami K.
europepmc   +1 more source

Novel drugs approved by the EMA, the FDA and the MHRA in 2025: A year in review

British Journal of Pharmacology, EarlyView.
Abstract In the 2025 novel drug mini‐review, one can take a full measure of the ingenuity that underlies current drug design and development, despite the year's smaller harvest (46 novel drugs) compared to 2024 (53) and 2023 (70). 54% of the novel drugs are first‐in‐class (FIC).
Andreas Papapetropoulos, Stavros Topouzis, Steve P. H. Alexander, Miriam M. Cortese‐Krott, Zsuzsanna Helyes, Kirill Martemyanov, Claudio Mauro, Nithyanandan Nagercoil, Reynold A. Panettieri Jr, Hemal H. Patel, Rainer Schulz, Barbara Stefanska, Gary J. Stephens, Nathalie Vergnolle, Xin Wang, Stephen Ward, Péter Ferdinandy   +16 more
wiley   +1 more source

Characterization of occupational exposure to air pollutants during asphalt milling and paving. [PDF]

Ann Work Expo Health
Hedmer M, Lovén K, Rex J, Nilsson CA, Polat M, Nøjgaard JK, Pagels J, Strandberg B, Hagvall L.   +8 more
europepmc   +1 more source

Cellular Signalling Networks in High Altitude Pulmonary Hypertension: From Canonical Pathways to Emerging Targets

Cell Proliferation, EarlyView.
This review elucidates the intricate cellular signalling networks involved in high‐altitude pulmonary hypertension (HAPH), integrating canonical pathways like HIF, MAPK and BMP with emerging targets such as Wnt/β‐catenin, Notch, Hippo‐YAP and IL‐6. It highlights potential therapeutic strategies targeting these pathways to mitigate vascular remodelling ...
Sheng Ding, Ju Chen, Zhaoyang Li, Yang Yu, Weijie Wang, Yan Liao, Jin Yang, Dianxiang Lu, Yujiang Fan   +8 more
wiley   +1 more source

Polycyclic aromatic hydrocarbons and polychlorinated biphenyls in tissue of mangrove Rhizophora mangle from the Colombian Caribbean. [PDF]

Environ Monit Assess
García-Meléndez L, Santos-Vásquez N, Campos-Campos NH, Sanjuan-Muñoz A, Mancera-Rodríguez NJ, Monroy M.   +5 more
europepmc   +1 more source

Polycyclic aromatic hydrocarbons (PAHs) enriching antibiotic resistance genes (ARGs) in the soils.

Environmental Pollution, 2017
Baowei Chen, Rong He, Ke Yuan, E. Chen, Lan Lin, Xin Chen, Sha Sha, Jianan Zhong, Li Lin, Lihua Yang, Ying Yang, Xiaowei Wang, S. Zou, Tiangang Luan   +13 more
semanticscholar   +1 more source

Immune cells composition in the skin and subcutaneous adipose tissue of patients with systemic sclerosis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Systemic sclerosis (SSc) is a rare, chronic autoimmune disease characterized by fibrosis of the skin and/or internal organs. Emerging evidence suggests that subcutaneous adipose tissue may contribute to systemic inflammation and fibrosis in SSc.
Marija Geroldinger‐Simić, Ana E. Aguilar González, Gerald Exler, Georg Stary   +3 more
wiley   +1 more source

Global burden and trends of tracheal, bronchus, and lung cancer attributed to occupational exposure to polycyclic aromatic hydrocarbons in regions with different sociodemographic index, 1990-2021. [PDF]

PLoS One
Lin J, Xie X, Zheng X, Shi H.
europepmc   +1 more source

PAH-Belastungsmonitoring [PDF]

, 2019
openaire   +1 more source