Results 231 to 240 of about 54,052 (308)

GCN2 in proteostasis: structural logic, signalling networks and disease

The FEBS Journal, EarlyView.
Threats to protein synthesis activate the kinase GCN2, initiating the integrated stress response (ISR). GCN2 is triggered by stalled ribosomes and uncharged tRNAs, which accumulate when amino acids are scarce. The ISR adjusts cellular physiology by promoting redox balance, protein quality control, and mitochondrial optimisation.
JiaYi Zhu, Stefan J. Marciniak
wiley   +1 more source

Chemical investigation of polycyclic aromatic hydrocarbon sources and associated health risks in PM_2.5 from Eastern India. [PDF]

Sci Rep
Subair MY, Karigowda, Habib G, Warsi AB, Imran M, Nabi MU.   +5 more
europepmc   +1 more source

PFAS Forensics, Part 2: Analytical Tools and Data Analysis for Source Attribution

Groundwater Monitoring &Remediation, EarlyView.
Abstract Successfully attributing per‐ and polyfluoroalkyl substances (PFAS) contamination to specific sources may require employing advanced analytical techniques and interpreting complex multivariate datasets. This paper, the second in a series on PFAS forensics, presents some of the analytical and data analysis tools practitioners use to identify ...
Taryn McKnight, Erica DiFilippo, Brian Drollette, Jeremiah Duncan, Dylan Eberle, Bernadette Flehmer, Andy Horn   +6 more
wiley   +1 more source

Microbial response and resistance mechanisms against diverse anthropogenic pollutants. [PDF]

Front Microbiol
Morkoç O, Esen Ö, Topaloğlu A, Çakar ZP.   +3 more
europepmc   +1 more source

A review of skin microbiome and new challenges to cosmetic microbiome‐friendly formulations

International Journal of Cosmetic Science, EarlyView.
Microbiome‐friendly concepts offer new perspectives for a healthy relationship between cosmetic use and the skin microbiome, especially the interaction of non‐biotic cosmetic ingredients with the skin, requiring further studies to clarify the dynamics between the skin microbiome and different classes of cosmetic ingredients.
Yasmin Rosa Santos, Newton Andréo‐Filho, Patricia Santos Lopes, Vânia Rodrigues Leite‐Silva   +3 more
wiley   +1 more source

Day-by-Day Ambient Determination of Nighttime Heterogeneous Oxidation of Particle-Phase Benzo[a]pyrene in an Urban Environment. [PDF]

Environ Sci Technol
Wang Q, Li Z, Huang Z, Zhu S, Li J, Qiao L, Zhou M, Huang D, Wang H, Fu Q, Yu H, Yu JZ.   +11 more
europepmc   +1 more source

Evaluating maturity of organic matter in hydrated C1 and CM‐like clasts and a dehydrated clast within a polymict eucrite and a howardite

Meteoritics &Planetary Science, EarlyView.
Abstract Volatile‐rich xenolithic clasts in different types of brecciated meteorites represent unique pristine solar system material. This study investigates the maturity and thermal history of organic matter using Raman spectroscopy and aqueous alteration effects using infrared spectroscopy in the matrix of 15 volatile‐rich clasts (C1 and CM‐like ...
Swarna Prava Das, Alessandro Maturilli, Aurélie Van den Neucker, Markus Patzek, Dipak Kumar Panda, Gopal K. Pradhan, Guneshwar Thangjam, Surya Snata Rout   +7 more
wiley   +1 more source

Oxygenated PAHs in Tokyo Bay sediments: distributional contrast with parent PAHs and their effect evaluations with fish embryos. [PDF]

Environ Monit Assess
Imamura K, Maehara A, Nakamura S, Uno S, Kokushi E.   +4 more
europepmc   +1 more source

Real‐World Treatment of Patients With Sinus Node Dysfunction and Heart Failure With Preserved Ejection Fraction

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background Permanent pacemaker (PPM) implantation is recommended in patients with sinus node dysfunction (SND). In patients with coexisting heart failure with preserved ejection fraction (HFpEF), clinicians may be hesitant to treat SND due to concerns about exacerbating heart failure.
Nicole Habel, Sarah Rosemas, Lucas Higuera, Patrick Zimmerman, Markus Meyer   +4 more
wiley   +1 more source

Microplastics as a Modifier of Polycyclic Aromatic Hydrocarbon (PAH) Toxicity: A Review on Context-Dependent Effects Across Organisms. [PDF]

Biology (Basel)
Arcadio CGLA, Maglupay JRU, Po AM, Pardillo JJB, Bacosa HP.   +4 more
europepmc   +1 more source