Results 211 to 220 of about 207,386 (342)

Tapinarof as a Therapeutic Aryl Hydrocarbon Receptor‐Modulating Agent in the Treatment of Atopic Dermatitis

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory dermatitis underpinned by Type 2 inflammation driven by cytokines such as IL‐4 and IL‐13. It is characterized by skin barrier dysfunction, Th2 immune deviation, and pruritus. While biologics and oral Janus kinase (JAK) inhibitors demonstrate high therapeutic efficacy by targeting cytokines that ...
Gaku Tsuji   +7 more
wiley   +1 more source

EPISTEMIC EXTRACTIVISM IN ENGAGED URBAN AND HOUSING RESEARCH: Implications and Counter‐measures

open access: yesInternational Journal of Urban and Regional Research, EarlyView.
Abstract What is ‘epistemic extractivism’, and how does it affect researchers who are engaged in urban and housing movements? This essay first explores the contexts of both engaged research and epistemic extractivism, clarifying their meanings and implications. It also disentangles the ethical and methodological risks posed by epistemic extractivism in
Miguel A. Martínez
wiley   +1 more source

Chiral Heptagon-Embedded Double [6]Helicenes via Scholl Reaction. [PDF]

open access: yesAngew Chem Int Ed Engl
Wang D   +6 more
europepmc   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

open access: yesAllergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter   +20 more
wiley   +1 more source

Use of parallel fluorescent confocal microscopy for detection of prostatic adenocarcinoma

open access: yesBJU International, EarlyView.
Objective To provide a histological catalogue and defined criteria for the diagnosis of prostatic adenocarcinoma and its variants using the fluorescent confocal microscope (FCM) platform. Methods A total of 22 radical prostatectomy specimens were serially sectioned and scanned with the FCM.
Kevin Clare   +13 more
wiley   +1 more source

Polycyclic aromatic hydrocarbons (PAHs) enriching antibiotic resistance genes (ARGs) in the soils.

open access: yesEnvironmental Pollution, 2017
Baowei Chen   +13 more
semanticscholar   +1 more source

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