Results 31 to 40 of about 35,290 (183)

Ultrasound-guided percutaneous laser cervical discectomy for intractable hiccups: A rare case report

open access: yesHeliyon, 2023
Background: Intractable hiccups serve no physiological purpose, but significantly reduce the quality of life. There are a variety of medications suggested for the treatment of persistent or intractable hiccups.
Jiahui Ma   +6 more
doaj   +1 more source

NEAT1 Promotes Epileptogenesis in Tuberous Sclerosis Complex

open access: yesAdvanced Science, EarlyView.
The primary neurological manifestations of tuberous sclerosis complex (TSC) are intractable epilepsy and intellectual disability. NEAT1 is differentially expressed in TSC‐related epilepsy and influences neuronal excitability by regulating the PI3K/AKT/mTOR signaling pathway.
Suhui Kuang   +8 more
wiley   +1 more source

A 92-Year-Old Man with Abdominal Pain Following Intractable Vomiting; a Photo Quiz

open access: yesArchives of Academic Emergency Medicine, 2019
A 92-year-old man with hypertension, chronic obstructive pulmonary disease (COPD), peptic ulcer disease and dementia presented to the emergency department with a 2-day history of abdominal pain in the left upper quadrant, distention, dry cough and ...
Chin-Chu Wu, Aming Chor-Ming Lin
doaj   +1 more source

Update on Interventional Management of Neuropathic Pain: A Delphi Consensus of the Spanish Pain Society Neuropathic Pain Task Force

open access: yesMedicina, 2022
Background and Objectives: Interventional management of neuropathic pain (NP) is available to the patients who do not obtain satisfactory pain relief with pharmacotherapy. Evidence supporting this is sparse and fragmented.
Ancor Serrano-Afonso   +5 more
doaj   +1 more source

Morphine Tolerance Gated through EZH2‐Mediated Suppression of Trpc5 in Spinal GABAergic Interneurons in Male Mice

open access: yesAdvanced Science, EarlyView.
Chronic morphine suppresses Trpc5 in spinal GABAergic interneurons via EZH2‐mediated histone modification, reducing Ca2+ influx and GABA release. TRPC5 activation enhances morphine analgesia, while EZH2 inhibition restores efficacy and reverses tolerance.
Li Wan   +9 more
wiley   +1 more source

Ureteral stent insertion in pregnants with intractable flank pain: A clinical experience

open access: yesSouthern Clinics of Istanbul Eurasia, 2019
INTRODUCTION[|]To evaluate the efficacy of JJ stent placement in pregnants with intractable flank pain [¤]METHODS[|]Pregnants with flank pain who referred to our clinic between January 2011 and March 2016 were retrospectively reviewed.
Utku Can   +4 more
doaj   +1 more source

The Reset Neurotomy within a Nonidentifiable Zone of Injury after Trauma

open access: yesPlastic and Reconstructive Surgery, Global Open, 2023
Summary:. Recent reconstructive approaches to peripheral nerve surgery have been directed toward active approaches; one such approach is nerve grafting the injured nerve segment.
Lauren L. Schnack, DPM, MS, AACFAS, FACPM   +3 more
doaj   +1 more source

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

open access: yesAdvanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

Longitudinal Pancreaticojejunostomy Reconstruction Following Pancreaticoduodenectomy for Patients With Concomitant Chronic Pancreatitis: How I Do It

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This report details a modified reconstructive technique, longitudinal pancreaticojejunostomy (LPJ), following pancreaticoduodenectomy (PD) for patients with both pancreatic head pathology and extensive chronic pancreatitis. This approach ensures wide‐area drainage of the remnant pancreatic duct, providing effective symptom relief and preserving long ...
Hideaki Sato   +4 more
wiley   +1 more source

Profiling Social Entrepreneurship Orientation Through Machine Learning Predictive Modeling

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study examines the prediction of Social Entrepreneurship Orientation (SEO) in youth using machine learning techniques to generate a robust predictive model. Drawing on a large cross‐country survey of European youth, results indicate that cognitive–attitudinal indicators—such as concern for environmental goals, purpose‐driven motivation ...
Ángel Peiró‐Signes   +2 more
wiley   +1 more source

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