Results 31 to 40 of about 35,661 (228)

Update on Interventional Management of Neuropathic Pain: A Delphi Consensus of the Spanish Pain Society Neuropathic Pain Task Force

Medicina, 2022
Background and Objectives: Interventional management of neuropathic pain (NP) is available to the patients who do not obtain satisfactory pain relief with pharmacotherapy. Evidence supporting this is sparse and fragmented.
Ancor Serrano-Afonso, Rafael Gálvez, Elena Paramés, Ana Navarro, Dolores Ochoa, Concepción Pérez-Hernández   +5 more
doaj   +1 more source

CircTspan3 Promotes Cartilage Development Through ANNEXIN A2‐Mediated Ferroptosis and Apoptosis Inhibition and Exosome‐Mediated Paracrine Signaling

Advanced Science, EarlyView.
This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan, Fengmei Zhang, Jiayan Zhong, Qian Gong, Nana Geng, Biao Kuang, Qiumei Lan, Miao Yi, Qiqi Zeng, Cheng Chen, Mengtian Fan, Chunliang Zhao, Deping Zeng, Yu Du, Mao Nie, Zhibiao Wang, Fengjin Guo   +16 more
wiley   +1 more source

Ureteral stent insertion in pregnants with intractable flank pain: A clinical experience

Southern Clinics of Istanbul Eurasia, 2019
INTRODUCTION[|]To evaluate the efficacy of JJ stent placement in pregnants with intractable flank pain [¤]METHODS[|]Pregnants with flank pain who referred to our clinic between January 2011 and March 2016 were retrospectively reviewed.
Utku Can, Murat Tuncer, Fehmi Narter, Kubilay Sabuncu, Kemal Sarıca   +4 more
doaj   +1 more source

The Reset Neurotomy within a Nonidentifiable Zone of Injury after Trauma

Plastic and Reconstructive Surgery, Global Open, 2023
Summary:. Recent reconstructive approaches to peripheral nerve surgery have been directed toward active approaches; one such approach is nerve grafting the injured nerve segment.
Lauren L. Schnack, DPM, MS, AACFAS, FACPM, Edgardo R. Rodriguez-Collazo, DPM, Stephanie A. Oexeman, DPM, AACFAS, DABPM, Andrew J. Costa, BS   +3 more
doaj   +1 more source

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

Advanced Science, EarlyView.
Molecularly imprinted polymeric nanocarriers (nanoMIPs) offer robust, antibody‐mimetic platforms to overcome the blood‐brain barrier. The article surveys nanoMIP design and ligand‐directed surface engineering that harness receptor‐mediated transcytosis, and highlights therapeutic and diagnostic applications in neurodegeneration, brain tumors and ...
Ranjit De, Shuliang Shi, Kyong‐Tai Kim
wiley   +1 more source

Engineering Ultrasound Contrast Agents for Targeted Therapeutics: A Theranostic Approach to Drug Delivery, Gene Therapy, and Immunomodulation

Advanced NanoBiomed Research, EarlyView.
Ultrasound contrast agents, including microbubbles and nanobubbles, transform imaging and targeted therapy through precise engineering of size, shell composition, and surface properties. This review explores how these innovations enable tissue‐specific delivery, enhance therapeutic efficacy, and extend applications from vascular imaging to tumor ...
Ashkan Seza, Kimia Mozahheb Yousefi, Sara Minaeian   +2 more
wiley   +1 more source

Risk factors for relapse in ANCA‐associated vasculitis among patients with relapse after induction of remission with rituximab

Arthritis &Rheumatology, Accepted Article.
Objective To determine risk factors for relapse of ANCA‐associated vasculitis (AAV) after re‐induction of remission with rituximab and discontinuation of maintenance therapy. Methods This is a post‐hoc analysis of the RITAZAREM clinical trial. Patients 15 years or older with AAV and a positive test for anti‐proteinase‐3 (PR3‐) or anti‐myeloperoxidase ...
Ellen Romich, Joshua F. Baker, Thomas R. Riley IV, Ian Green, Rennie L. Rhee, Carol A. McAlear, Ulrich Specks, Rona M. Smith, David R. Jayne, Peter A. Merkel, for the RITAZAREM Investigators   +10 more
wiley   +1 more source

Profiling Social Entrepreneurship Orientation Through Machine Learning Predictive Modeling

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study examines the prediction of Social Entrepreneurship Orientation (SEO) in youth using machine learning techniques to generate a robust predictive model. Drawing on a large cross‐country survey of European youth, results indicate that cognitive–attitudinal indicators—such as concern for environmental goals, purpose‐driven motivation ...
Ángel Peiró‐Signes, Colin Donaldson, Marival Segarra‐Oña   +2 more
wiley   +1 more source

Mesial temporal lobe epilepsy with hippocampal sclerosis: Seizure, neuropsychological, and quality of life outcomes of 100 patients treated with trans‐anterior T1 selective amygdalohippocampectomy

Epileptic Disorders, EarlyView.
Abstract Objective For mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE with HS), laser interstitial thermal therapy has recently been increasingly used. At our institute, however, selective amygdalohippocampectomy by a trans‐anterior T1 subpial approach (trans‐anterior T1 SAH) has been used for MTLE with HS. Here, we examined the seizure,
Naotaka Usui, Hiroshi Ogawa, Akihiko Kondo, Kazumi Matsuda, Mitsuru Hashiguchi, Taro Okumura, Yuuki Ishida, Norihiko Kawaguchi, Takashi Matsudaira, Kentaro Tokumoto, Takuji Nishida, Katsumi Imai   +11 more
wiley   +1 more source

Eosinophilic Jejunitis Presenting as Intractable Abdominal Pain

Case Reports in Gastroenterology, 2014
Eosinophilic gastroenteritis is an uncommon disease characterized by eosinophilic infiltration of the gastrointestinal tract. The clinical manifestations are related to the layer(s) and extent of the bowel involved.
Zeynel Mungan, Tan Attila, Yersu Kapran, Ilyas Pinar Tokatli, Zeynep Unal   +4 more
doaj   +1 more source