Results 31 to 40 of about 89,513 (282)

OPEN ANTERIOR CORDOTOMY AS A POSSIBLE TECHNIQUE FOR PAIN RELIEF IN CANCER PATIENT: AN EXPERIENCE WITH SEVEN CASES [PDF]

open access: yesActa Medica Iranica, 1996
Seven patients who had intractable pain of the pelvis and lower extremities were scheduled for cordotomy of the spinothalamic tracts after preliminary investigations.
Sheikhrezai   +4 more
doaj   +1 more source

Surgery for Spine Disease and Intractable Pain

open access: yesBrain Sciences, 2020
Painful conditions, particularly due to head pain, spinal disease, and neuropathic pain, are highly prevalent in modern society, resulting in a significant impact on the individual due to the disability of the condition and the direct cost of associated ...
Warren Boling
doaj   +1 more source

PATTERN: Pain Assessment for paTients who can't TEll using Restricted Boltzmann machiNe. [PDF]

open access: yes, 2016
BackgroundAccurately assessing pain for those who cannot make self-report of pain, such as minimally responsive or severely brain-injured patients, is challenging. In this paper, we attempted to address this challenge by answering the following questions:
Cheng, Samuel   +4 more
core   +2 more sources

Relief of interstitial cystitis/bladder pain syndrome by spinal cord stimulation

open access: yesInterdisciplinary Neurosurgery, 2022
Interstitial cystitis/bladder pain syndrome is a chronic, visceral pain syndrome that affects one in every twenty women. Sacral roots stimulation is successfully used to mitigate pain and urinary symptoms when non surgical treatments are ineffective.
Nazih Moufarrij, Miranda Huebner
doaj   +1 more source

Defining refractory pain in cancer for clinicians and researchers [PDF]

open access: yes, 2012
Managing pain in people with cancer remains a challenge, especially in those referred to as having refractory pain. But what is refractory or intractable pain?
Currow, David Christopher   +2 more
core   +1 more source

Targeted Anti‐IL‐1 Immunomodulatory Therapy in Pediatric Onset PPP1R13L‐Related Arrhythmogenic Cardiomyopathy

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal recessive loss‐of‐function variants in PPP1R13L cause an ultra‐rare cardiocutaneous syndrome characterized by rapidly progressive arrhythmogenic cardiomyopathy (ACM). PPP1R13L encodes iASPP, which has two potentially overlapping mechanisms driving ACM as both a regulator of NFκB‐mediated inflammation and a binding partner within the ...
Aaron Renberg   +9 more
wiley   +1 more source

Phenol Neurolysis in Pain and Palliative Medicine. [PDF]

open access: yesPain Pract
ABSTRACT Background Pain is a common symptom in palliative care and affects patients' quality of life considerably. Standard analgesics are sometimes insufficient and are associated with substantial side effects. Neurolysis, the targeted destruction of nerves using thermal or chemical agents, offers an additional option for managing localized pain in ...
Creemers JHA   +6 more
europepmc   +2 more sources

Case of Monostotic Fibrous Dysplasia in the hand [PDF]

open access: yes, 2002
A case of monostotic fibrous dysplasia in the proximal phalanx of an otherwise healthy, twenty-five year old is discussed. Fibrous dysplasia in the hand is rarely seen. Our patient presented with a swelling in his proximal phalanx.
Attard, Gerhardt   +2 more
core  

Refractory chronic migraine. a consensus statement on clinical definition from the European Headache Federation [PDF]

open access: yes, 2014
The debate on the clinical definition of refractory Chronic Migraine (rCM) is still far to be concluded. The importance to create a clinical framing of these rCM patients resides in the complete disability they show, in the high risk of serious adverse ...
C. Lampl   +8 more
core   +2 more sources

Sex as a biological variable in nonclinical studies: Bridging scientific rigor, animal welfare, and regulatory expectations

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Sex as a biological variable (SABV) is a critical determinant of pharmacokinetics, pharmacodynamics, and toxicity in nonclinical studies. This review highlights how inappropriate neglect of sex differences compromises animal welfare, scientific reproducibility, and regulatory compliance.
Kenta Onuma   +2 more
wiley   +1 more source

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