Results 71 to 80 of about 6,843,138 (404)

Player agency in interactive narrative: audience, actor & author [PDF]

, 2007
The question motivating this review paper is, how can computer-based interactive narrative be used as a constructivist learn- ing activity? The paper proposes that player agency can be used to link interactive narrative to learner agency in ...
Hammond, S., Pain, H., Smith, Tim J.
core  

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Extracting Physical Information from the Voigt Profile Using the Lambert W Function

Plasma
Spectral line shapes are a key ingredient of hot-plasma opacity calculations. Since resorting to elaborate line-shape models remains prohibitive for intensive opacity calculations involving ions in different excitation states, with L, M, etc., shells are
Jean-Christophe Pain
doaj   +1 more source

The IASP classification of chronic pain for ICD-11: chronic primary pain

Pain, 2019
This article describes a proposal for the new diagnosis of chronic primary pain (CPP) in ICD-11. Chronic primary pain is chosen when pain has persisted for more than 3 months and is associated with significant emotional distress and/or functional ...
M. Nicholas, J. Vlaeyen, W. Rief, A. Barke, Q. Aziz, R. Benoliel, Milton L Cohen, S. Evers, M. Giamberardino, A. Goebel, Beatrice Korwisi, S. Perrot, P. Svensson, Shuu-Jiun Wang, R. Treede   +14 more
semanticscholar   +1 more source

Prevalence and time course of post-stroke pain: A multicenter prospective hospital-based study [PDF]

, 2015
OBJECTIVE: Pain prevalence data for patients at various stages after stroke. DESIGN: Repeated cross-sectional, observational epidemiological study. SETTING: Hospital-based multicenter study.
Barbanti, Piero, Bovi, Paolo, Candeloro, E, Cavallini, Anna, Cruccu, Giorgio, Iosa, Marco, Mancini, Alessia, Mancuso, Mauro, Monaco, Serena, Paolucci, Stefano, Pieroni, Alessio, Pieroni, Alessio, Recchia, Serena, Sessa, Maria, Strambo, Davide, Tinazzi, Michele, Toni, Danilo, Truini, Andrea   +17 more
core   +1 more source

Peripheral nerve block anaesthesia and postoperative pain in acute ankle fracture surgery: the AnAnkle randomised trial [PDF]

, 2021
Rune Sort, Stig Brorson, Ismail Gögenür, Lasse L. Hald, Jesper K. Nielsen, N. Salling, Sine Hougaard, Nicolai Bang Foss, Peter Toft Tengberg, Tobias Wirenfeldt Klausen, Ann Merete Møller   +10 more
openalex   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Pain outcomes in patients with bone metastases from advanced cancer: assessment and management with bone-targeting agents [PDF]

, 2014
Bone metastases in advanced cancer frequently cause painful complications that impair patient physical activity and negatively affect quality of life. Pain is often underreported and poorly managed in these patients.
A Kretzschmar, A Mañas, A Wardley, AT Stopeck, C Langer, C Logothetis, Charles S. Cleeland, CI Ripamonti, CJ Logothetis, CS Cleeland, CS Cleeland, D Henry, D Patrick, DH Henry, DL Patrick, Donald L. Patrick, DS Ernst, E Basch, E Chow, F Saad, F Saad, G Apolone, G Cartenì, G Storto, GN Hortobagyi, GN Hortobagyi, HI Scher, JJ Body, JJ Body, K Altundag, K Fizazi, K Harris, Katarina Öhrling, KC Chung, KP Weinfurt, KP Weinfurt, L Atahan, L Costa, L Fallowfield, Lesley Fallowfield, LS Matza, LS Rosen, LS Rosen, LS Rosen, M Huisman, M Martin, M Tomblyn, MG Lam, MJ Fisch, N Kohno, N Takeda, P Hoskin, P Hoskin, R Moos von, R Moos von, Rachel Wei, RE Coleman, RE Coleman, RE Coleman, RH Dworkin, RL Theriault, Roger von Moos, S Deandrea, S Nilsson, S Vadhan-Raj, SD Mathias, T Kijima, V Vassiliou, V Vassiliou, Yi Qian   +69 more
core   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Salutary Effects of Overexpression of Rsm22, an Assembly Factor for the Mitochondrial Ribosome, on Frataxin/Yfh1 Depletion Phenotypes in Saccharomyces cerevisiae

Biomolecules
Frataxin is a component of the iron–sulfur (Fe-S) cluster assembly complex in mitochondria, and deficiency is associated with Friedreich ataxia (FA). The yeast homolog Yfh1 resembles and cross-complements with its human equivalent, and frataxin bypass ...
Ashutosh K. Pandey, Pratibha Singh, Jayashree Pain, Andrew Dancis, Debkumar Pain   +4 more
doaj   +1 more source