Results 81 to 90 of about 3,120,303 (258)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Sum rules for permutations with fixed points involving Stirling numbers of the first kind

Indonesian Journal of Combinatorics
We propose sum rules for permutations pn(k) of the ensemble {1,2,...,n} with k fixed points, in the form of partial sums of their moments. The corresponding identities involve Stirling numbers of the first kind s(q,r).
Jean-Christophe Pain
doaj   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Ensuring transparency and minimization of methodologic bias in preclinical pain research: PPRECISE considerations [PDF]

, 2015
There is growing concern about lack of scientific rigor and transparent reporting across many preclinical fields of biological research. Poor experimental design and lack of transparent reporting can result in conscious or unconscious experimental bias ...
Lee, N, Svensson, CI, Levine, J, Jensen, MP, Mogil, JS, Stone, L, McMahon, SB, Gover, TD, Turk, DC, Evans, S, Gewandter, JS, Handwerker, H, Basbaum, AI, Ross, SE, Currie, GL, Iyengar, S, Andrews, NA, McDermott, MP, Latrémolière, A, Huang, W, Porreca, F, Seal, RP, Sena, ES, Eisenach, JC, Kennedy, JD, Lidster, K, Machin, I, Silva, E, Woolf, CJ, Price, TJ, Scherrer, G, Whiteside, G, Dworkin, RH, Rice, AS   +33 more
core   +1 more source

A pilot study of reliability and validity of Turkish version of West Haven-Yale Multidimensional Pain Inventory in patients with low back pain [PDF]

, 2020
Background: West Haven-Yale Multidimensional Pain Inventory (WHYMPI), used in the evaluation of patients with chronic pain including behavioral and cognitive assessment, is a multidimensional pain scale consisting of three main sections and 12 subscales.
Ertunç Gülçelik, Gönül, Özbek, Hanefi, Yıldız Özer, Aysel, Malkoç, Melih   +3 more
core   +1 more source

The Effect of Tramadol Versus Sufentanil on Controlling Postoperative Pain for Men Who Smoke and Do Not Smoke: A Randomized Clinical Trial

, 2022
Background: Smoking behavior alters the analgesic threshold, which challenges postoperative pain management for patients who smoke.Objectives: We aimed to assess the analgesic efficacy of tramadol versus sufentanil in relieving postoperative pain for ...
Wei, Kai, Lu, Zhi-jie, Bi, Yanzhi, Shen, Ling, Chen, Qianbo, Liu, Yantao, Xu, Huihong, Hu, Li, Miao, Xuerong, Wu, Cheng   +9 more
core   +3 more sources

Salutary Effects of Overexpression of Rsm22, an Assembly Factor for the Mitochondrial Ribosome, on Frataxin/Yfh1 Depletion Phenotypes in Saccharomyces cerevisiae

Biomolecules
Frataxin is a component of the iron–sulfur (Fe-S) cluster assembly complex in mitochondria, and deficiency is associated with Friedreich ataxia (FA). The yeast homolog Yfh1 resembles and cross-complements with its human equivalent, and frataxin bypass ...
Ashutosh K. Pandey, Pratibha Singh, Jayashree Pain, Andrew Dancis, Debkumar Pain   +4 more
doaj   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Ciclo de Vida Organizacional e Comunicação Estratégica: Efeitos nas Previsões dos Analistas

RAC: Revista de Administração Contemporânea
Objetivo: este estudo investiga a influência das fases do ciclo de vida organizacional na relação das divulgações voluntárias corporativas com a assertividade das previsões de lucros feitas por analistas financeiros.
Patrícia Pain, Márcia Bianchi
doaj   +1 more source

ZEST: A Fast Code for Simulating Zeeman-Stark Line-Shape Functions

Atoms, 2018
We present the ZEST code, dedicated to the calculation of line shapes broadened by Zeeman and Stark effects. As concerns the Stark effect, the model is based on the Standard Lineshape Theory in which ions are treated in the quasi-static approximation ...
Franck Gilleron, Jean-Christophe Pain
doaj   +1 more source