Results 81 to 90 of about 8,131,393 (399)

The measurement of pain, 1945–2000 [PDF]

Journal of Pain and Symptom Management, 2005
Three strands of activity can be identified in the history of pain measurement. The first, psychophysics, dates back to the nineteenth century and measures the effect of analgesia by quantifying the noxious stimulation required to elicit pain, as well as the maximum stimulation tolerated.
Noble, B., Clark, D., Meldrum, M., Have, H.A.M.J. ten, Seymour, J., Winslow, M., Paz, S.   +6 more
openaire   +4 more sources

Long‐Term Evaluation of Givinostat in Duchenne Muscular Dystrophy, and Natural History Comparisons

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This ongoing, open‐label extension study is evaluating the long‐term safety, tolerability, and efficacy of givinostat, a Class I and II histone deacetylase inhibitor, in patients with Duchenne muscular dystrophy (DMD). Methods The recruited patients completed one of two prior clinical studies (one Phase 2 and one Phase 3 [EPIDYS ...
Craig M. McDonald, Michela Guglieri, Dragana Vučinić, Gyula Acsadi, John F. Brandsema, Claudio Bruno, Erika L. Finanger, Amy Harper, Mercedes Lopez Lobato, Riccardo Masson, Nuria Muelas, Francina Munell, Yoram Nevo, Yann Péréon, Han Phan, Valeria A. Sansone, Mariacristina Scoto, Tracey Willis, Richard S. Finkel, Krista Vandenborne, Sara Cazzaniga, Silvia Montrasio, Federica Alessi, Paolo Bettica, Eugenio Mercuri, for the Givinostat Study 51 Investigators, the Cooperative International Neuromuscular Research Group (CINRG) Duchenne Natural History Study (DNHS) Investigators, the ImagingDMD Investigators, Enrico Bertini, Giacomo Pietro Comi, Eugenio Maria Mercuri, Giuseppe Vita, Sonia Messina, Claudio Bruno, Riccardo Masson, Valeria Sansone, Nathalie Goemans, Liesbeth De Waele, Laurent Servais, Teresa Gidaro, Odile Boespflug‐Tanguy, Yann Péréon, Jessika Johannsen, Astrid Blaschek, Ulrike Schara‐Schmidt, Erik Niks, Imelda de Groot, Saskia Houwen‐van Opstal, Andres Nascimento, Juan Jesus Vilchez, Nuria Muelas, Francina Munell, Marcos Madruga Garrido, Mercedes Lopez Lobato, Michaela Guglieri, Tracey Willis, Stefan Spinty, Daniel Hawcutt, Mariacristina Scoto, Jean K. Mah, Laura McAdam, Kathryn Selby, Katherine Mathews, Craig McDonald, Craig Zaidman, Barry Byrne, John Brandsema, Gyula Acsadi, Chamindra Laverty, Amy Harper, Erika Finanger, Han Phan, Yoram Nevo, Vedrana Milic Rasic, Dragana Vucinic   +74 more
wiley   +1 more source

The effect of diclofenac mouthwash on periodontal postoperative pain

Dental Research Journal, 2011
Background: The need to relieve pain and inflammation after periodontal surgery and the side effects of systemic drugs and advantages of topical drugs, made us to evaluate the effect of Diclofenac mouthwash on periodontal postoperative pain.
Jaber Yaghini, Ahmad Moghareh Abed, Seyed Abolfazl Mostafavi, Najmeh Roshanzamir   +3 more
doaj  

Core outcome measurement instruments for clinical trials in nonspecific low back pain

Pain, 2017
To standardize outcome reporting in clinical trials of patients with nonspecific low back pain, an international multidisciplinary panel recommended physical functioning, pain intensity, and health-related quality of life (HRQoL) as core outcome domains.
Alessandro Chiarotto, M. Boers, R. Deyo, R. Buchbinder, Terry P. Corbin, L. Costa, N. Foster, M. Grotle, B. Koes, F. Kovacs, C. Lin, C. Maher, A. Pearson, W. Peul, M. Schoene, D. Turk, M. V. van Tulder, C. Terwee, R. Ostelo   +18 more
semanticscholar   +1 more source

Cultural responses to pain in UK children of primary school age: a mixed-methods study. [PDF]

, 2014
Pain-measurement tools are often criticized for not addressing the influence of culture and ethnicity on pain. This study examined how children who speak English as a primary or additional language discuss pain.
American Academy of Pediatrics: American Pain Society, Azize, Bates, Bochner, Bonham, Brooks-Brunn, Coyne, Creswell, Doyle, Drendel, Dunn, Edwards, Engel, Espinosa, Fortier, Green, Hadjistavropoulos, Hallström, Hoppe, Hornberger, Koffman, Liossi, Lollar, McCaffery, Miller, Parke, Perez, Schieffelin, Stalnikowicz, Stanford, Subhashini, Taylor, Van Maanen, Woodrow, Zinke   +34 more
core   +3 more sources

Chronic Pain in Parkinson’s Disease: Prevalence, Sex Differences, Regional Anatomy and Comorbidities

Annals of Clinical and Translational Neurology, EarlyView.
Chronic pain affected 66.2% of 10,631 individuals with Parkinson's disease, with higher prevalence and severity in females. Pain most often involved the buttocks, lower back, neck, and knees, and was linked to depression, sleep disorders, and osteoarthritis.
Natalia S. Ogonowski, Freddy Chafota, Fangyuan Cao, Amanda Wei Yin Lim, Victor Flores‐Ocampo, Santiago Díaz‐Torres, Zuriel Ceja, Luis M. García‐Marín, Scott F. Farrell, Kishore R. Kumar, Jane Alty, George D. Mellick, Trung Thành Ngô, Miguel E. Rentería   +13 more
wiley   +1 more source

Pre‐Diagnostic Features of Multiple Sclerosis in a Diverse UK Cohort: A Nested Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Many patients with Multiple Sclerosis (MS) experience nonspecific symptoms prior to diagnosis. This period—the 'MS prodrome'—has been described in socio‐economically homogeneous cohorts to date. It remains unclear to what extent events prior to an MS diagnosis differ according to social determinants of health. Methods We conducted a
Pooja Tank, Benjamin M. Jacobs, Jonathan Bestwick, Ruth Dobson   +3 more
wiley   +1 more source

Pressure pain endurance in women with fibromyalgia

Revista Dor
BACKGROUND AND OBJECTIVES:Fibromyalgia syndrome is a chronic condition causing spontaneous widespread pain associated with hypersensitivity. This study aimed at investigating the pressure pain endurance in women with fibromyalgia syndrome to determine ...
Rodrigo Pegado de Abreu Freitas, Sandra Cristina de Andrade, Ranulfo Fiel Pereira Pessoa de Carvalho, Maria Bernardete Cordeiro de Sousa   +3 more
doaj   +1 more source

Long COVID in People With Multiple Sclerosis and Related Disorders: A Multicenter Cross‐Sectional Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Managing long COVID in people with multiple sclerosis and related disorders (pwMSRD) is complex due to overlapping symptoms. To address evidence gaps, we evaluated long COVID susceptibility in pwMSRD versus controls and its associations with multi‐domain function and disability.
Chen Hu, Jiyeon Son, Lindsay McAlpine, Elizabeth L. S. Walker, Megan Dahl, Emily Song, Sugeidy Ferreira Brito, Katelyn Kavak, Kaho Onomichi, Amit Bar‐Or, Christopher Perrone, Claire S. Riley, Bianca Weinstock‐Guttman, Philip L. De Jager, Erin E. Longbrake, Zongqi Xia   +15 more
wiley   +1 more source

Measuring troublesomeness of chronic pain by location [PDF]

BMC Musculoskeletal Disorders, 2006
Abstract Background Current measures of pain assess the relative contribution of pain in different body regions to the overall impact of pain. We developed a series of questions to measure the relative 'troublesomeness' of pain in different body regions (the "troublesomeness grid").
Parsons, S, Carnes, D, Pincus, Tamar, Foster, N, Breen, A, Vogel, S, Underwood, M   +6 more
openaire   +13 more sources