Results 81 to 90 of about 929,846 (313)

The reliability and validity of a designed setup for the assessment of static back extensor force and endurance in older women with and without hyperkyphosis. [PDF]

, 2018
ObjectiveThe purpose of this study was to investigate the intra-rater reliability and validity of a designed load cell setup for the measurement of back extensor muscle force and endurance.ParticipantsThe study sample included 19 older women with ...
Akbarzadeh Baghban, Alireza, Katzman, Wendy, Khalkhali Zavieh, Minoo, King, Nicole, Manshadi, Farideh Dehghan, Rahimi, Abbas, Roghani, Taybeh, Talebian, Saeed   +7 more
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Pain measurement in arthritis [PDF]

Arthritis & Rheumatism, 1993
AbstractObjective. This paper reviews the major pain measurement methods used with adult patients with rheumatoid arthritis, osteoarthritis, and fibromyalgia.Methods and Results. The most frequently used measures are numerical and verbal rating (category) scales of pain intensity and affect.
openaire   +2 more sources

Penatalaksaan Terapi Latihan Pada Kondisi Post Caesarean Section Di Rsud Dr. Moewardi Surakarta [PDF]

, 2015
Background: Caesarean section is a surgery with making an incision in the abdominal wall as the way out of the baby. With a problematic form of pain, spasm, decreased range of motion, decrease in abdominal muscle strength, and decreased functional ...
, Yulisna Mutia Sari, SSt. Ft, M. Sc (GRS), Lestari, Atika Norwida   +1 more
core   +1 more source

Meta-analysis and systematic review of skin graft donor-site dressings with future guidelines. [PDF]

, 2018
Background: Many types of split-thickness skin graft (STSG) donor-site dressings are available with little consensus from the literature on the optimal dressing type. The purpose of this systematic review was to analyze the most recent outcomes regarding
Alwaal, Assadian, Baser, Begg, Blount, Brown, Brölmann, Cheesborough, Chung, Cigna, Demirtas, Dickersin, Druery, Fearmonti, Feldman, Fernandes de Carvalho, Ferreira, Ghieh, Goertz, Haith, Hasatsri, Hassanpour, Healy, Iwuagwu, Jadad, Junker, Kaiser, Konieczynska, Konieczynska, Konieczynska, Lairet, Liu, Lohsiriwat, Massand, McCartan, Metelmann, Moher, Muangman, Petruzzelli, Polfer, Potocká, Quinn, Rakel, Ratner, Salehi, Selig, Serino, Singh, Siritientong, Soltan Dallal, Tan, Tanaka, Vaghardoost, Vejdan, Villa-Camacho, Voineskos, Wiechula, Wisely, Zidan   +58 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Validation of the West Haven-Yale Multidimensional Pain Inventory (WHYMPI) for Iranian Patients with Chronic Pain

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2007
Background and Objectives: This study aimed to validate the West Haven-Yale Multidimensional Pain Inventory (WHYMPI) for Iranian patients with chronic pain.
SM Mirzamani, A Safari, MT Holisaz, A Sadidi   +3 more
doaj  

Tradução e adaptação transcultural de duas escalas para avaliação da dor em crianças e adolescentes Cross-cultural adaptation and translation of two pain assessment tools in children and adolescents

Jornal de Pediatria, 2008
OBJETIVO:Traduzir, retrotraduzir e adaptar culturalmente o conteúdo da Face, Legs, Activity, Cry, Consolability (FLACC) e da Escala de Faces Revisada (FPS-R) para avaliação da dor em crianças escolares e adolescentes brasileiros.
Flavia Claro da Silva, Luiz Claudio Santos Thuler   +1 more
doaj   +1 more source