Results 71 to 80 of about 4,428,726 (375)

Pharmacogenomics for personalized pain medicine

Acta Anaesthesiologica Taiwanica, 2016
Pharmacogenomics aims to unravel the way that human genetic variation affects drug efficacy and toxicity. Genome-wide association studies and candidate gene findings suggest that genetic approaches may help choose the most appropriate drug and dosage while preventing adverse drug reactions (ADRs). Pain is an unpleasant feeling that usually results from
Tai-Ming Ko, Tai-Ming Ko, Jer-Yuarn Wu, Jer-Yuarn Wu, Chih Shung Wong, Yuan-Tsong Chen, Yuan-Tsong Chen   +6 more
openaire   +3 more sources

Enhancing patient engagement in cancer research: a focus on patient‐centric approaches to scientific discovery

Molecular Oncology, EarlyView.
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda, Marina Reguero, Vanesa Abón, Marta Puyol   +3 more
wiley   +1 more source

A Full Transformer-based Framework for Automatic Pain Estimation using Videos [PDF]

2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)
The automatic estimation of pain is essential in designing an optimal pain management system offering reliable assessment and reducing the suffering of patients. In this study, we present a novel full transformer-based framework consisting of a Transformer in Transformer (TNT) model and a Transformer leveraging cross-attention and self-attention blocks.
arxiv   +1 more source

Comparison of preoxygenation efficiency measured by the oxygen reserve index between high-flow nasal oxygenation and facemask ventilation: a randomised controlled trial

BMC Anesthesiology, 2023
Background High-flow nasal oxygenation and the oxygen reserve index (ORI), which is a non-invasive and innovative modality that reflects the arterial oxygen content, are used in general anaesthesia.
Sujung Park, So Yeon Kim, Min-Soo Kim, Wyun Kon Park, Hyo-Jin Byon, Hyun Joo Kim   +5 more
doaj   +1 more source

HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4

FEBS Open Bio, EarlyView.
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang, Yukun Xu, Yujia Li, Yiming Pang, Xueting Ding, Raorao Zhou, Dan Liang, Xianda Che, Yuanyu Zhang, Chunfang Wang, Wenjin Li, Pengcui Li   +11 more
wiley   +1 more source

Evidence from web-based dietary search patterns to the role of B12 deficiency in chronic pain [PDF]

, 2017
Profound vitamin B12 deficiency is a known cause of disease, but the role of low or intermediate levels of B12 in the development of neuropathy and other neuropsychiatric symptoms as well as the relationship of eating meat and B12 levels is unclear.
arxiv   +1 more source

Statistical Applications in Pain Management: A Review [PDF]

arXiv, 2023
Chronic pain is a widespread and debilitating condition that affects millions of individuals worldwide. Recent research has unveiled a connection between chronic pain and epigenetic processes, shedding light on the complex interplay between genetics, environment, and pain perception.
arxiv  

Anesthesia in a Patient with Potocki–Lupski Syndrome

Case Reports in Anesthesiology, 2021
Introduction. Potocki–Lupski syndrome (PTLS) is a rare disease caused by the duplication of a small segment of chromosome 17 (17p11.2). The clinical presentation of this syndrome is quite variable and includes hypotonia, failure to thrive, oropharyngeal ...
Songhyun Kim, Yunhee Lim, In-Jung Jun, Byunghoon Yoo, Kye-Min Kim   +4 more
doaj   +1 more source

Characterisation of the role played by ELMO1, GPR141 and the intergenic polymorphism rs918980 in Fuchs' dystrophy in the Indian population

FEBS Open Bio, EarlyView.
This study reports the upregulation of ELMO1 and GPR141 in human Fuchs' endothelial corneal dystrophy (FECD) corneal endothelium and ultraviolet A‐induced FECD mice model. A genetic association of an intergenic single nucleotide polymorphism rs918980 present between both genes is observed with FECD in the Indian population.
Susmita Sharma, Samar Kumar Basak, Sujata Das, Debasmita Pankaj Alone   +3 more
wiley   +1 more source

VR for Acupuncture? Exploring Needs and Opportunities for Acupuncture Training and Treatment in Virtual Reality [PDF]

arXiv, 2023
Acupuncture is a form of medicine that involves inserting needles into targeted areas of the body and requires knowledge of both Traditional Chinese Medicine (TCM) and Evidence-Based Medicine (EBM). The process of acquiring such knowledge and using it for practical treatment is challenging due to the need for a deep understanding of human anatomy and ...
arxiv