Results 201 to 210 of about 281,000 (258)

Single‐Cell Reveal GALNT7‐Dependent Ferroptosis Suppression as a Mechanism of Immunotherapy Resistance in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
Integrated clinical and mechanistic analyses identify GALNT7 as a ferroptosis‐suppressive regulator associated with immunotherapy resistance in non‐small cell lung cancer. GALNT7 depletion promotes lipid peroxidation, mitochondrial dysfunction, and ferroptosis, enhances CD8+ T‐cell activation and IFN‐γ production, and sensitizes tumors to PD‐1 blockade,
Jiadi Gan, Qian Zheng, Deng Liu, Ruichao Nie, Menglin Yao, Xiaolong Tang, Renjie Xu, Jinghong Xian, Wenjun Meng, Wenxin Luo, Dan Liu, Guiyi Ji   +11 more
wiley   +1 more source

Gender Differences in Pain Threshold, Unpleasantness, and Descending Pain Modulatory Activation Across the Adult Life Span: A Cross Sectional Study. [PDF]

J Pain
Failla MD, Beach PA, Atalla S, Dietrich MS, Bruehl S, Cowan RL, Monroe TB.   +6 more
europepmc   +1 more source

Comparing The Effects of Compression Contrast Therapy and Dry Needling on Muscle Functionality, Pressure Pain Threshold, and Perfusion after Isometric Fatigue in Forearm Muscles of Combat Sports Athletes: A Single-Blind Randomized Controlled Trial. [PDF]

J Sports Sci Med
Kużdżał A, Clemente FM, Kawczyński A, Ryszkiel I, Trybulski R.   +4 more
europepmc   +1 more source

Thresholds of pain: photography and pain communication

, 2017
Padfield, Deborah G, Zakrzewska, Joanna M   +1 more
openaire   +1 more source

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Spontaneous pain, pain threshold, and pain tolerance in Parkinson’s disease

Journal of Neurology, 2010
The mechanisms underlying pain in Parkinson's disease (PD) are unclear. Although a few studies have reported that PD patients may have low pain threshold and tolerance, none could accurately assess whether there was a correlation between sensory thresholds and demographic/clinical features of PD patients.
Sandro Zambito Marsala, Michele Tinazzi, Antonio Fiaschi   +2 more
exaly   +6 more sources

Experimental changes in pain threshold and severe pain threshold for electrically induced pain

Journal of Psychosomatic Research, 1990
Pain and severe pain thresholds were measured in groups of 15 (Experiment 1) and 20 (Experiment 2) normal volunteers. In Experiment 1, the subjects underwent a series of ten constant level, painful stimuli each of 10 sec duration at an arbitrarily chosen level between the thresholds. This level was recorded.
J L, Collier, B M, Mehta, F G, Spear
openaire   +2 more sources

Pain thresholds are not elevated in trichotillomania

Biological Psychiatry, 1994
The current study investigates whether trichotillomania is characterized by a general hypoalgesia, which might allow for continued pulling hair due to the lack of aversive consequences and attention directing qualities of ...
G A, Christenson, N C, Raymond, P L, Faris, R D, McAllister, S J, Crow, L A, Howard, J E, Mitchell   +6 more
openaire   +2 more sources

Behavioral Measures of Pain Thresholds

Current Protocols in Mouse Biology, 2011
AbstractPain afflicts a fifth of the population, and animal models have proven useful in target validation and analgesic drug development. Thresholds to pain are tested by applying a sensory stimulus, such as heat or pressure, and observing the resulting withdrawal behavior.
Michael S, Minett, Kathryn, Quick, John N, Wood   +2 more
openaire   +2 more sources

Relationship of Anxiety With Pain Threshold

The Journal of Psychology, 1967
(1967). Relationship of Anxiety With Pain Threshold. The Journal of Psychology: Vol. 66, No. 2, pp. 181-183.
A, Bronzo, G, Powers
openaire   +2 more sources

Pain Tolerance Threshold and Pain Perception Threshold: Clinical and Experimental Studies

Clinics in Rheumatic Diseases, 1979
Many methods have been used to study pain experimentally. They make use of various noxious stimuli - heat, pressure, ischaemia, electrical discharge, or the injection of chemical pain mediators. They give rise to phasic or tonic pain and enable us to make fully or partially objective assessments of the pain perception threshold or the pain tolerance ...
openaire   +2 more sources