Results 91 to 100 of about 176,534 (288)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Agreeable smellers and sensitive neurotics - correlations among personality traits and sensory thresholds

, 2011
Correlations between personality traits and a wide range of sensory thresholds were examined. Participants (N = 124) completed a personality inventory (NEO-FFI) and underwent assessment of olfactory, trigeminal, tactile and gustatory detection thresholds,
Johnston Amy N. B., Croy Ilona, Croy, I, Springborn, Maria, Loetsch, Joern, Thomas Hummel, Johnston, Amy, Jörn Lötsch, Spingborn, M, Johnston, Amy N. B., Springborn Maria, Hummel Thomas, Amy N B Johnston, Maria Springborn, Lötsch, J, Johnston, A, Lötsch Jörn, Hummel, Thomas, Ilona Croy, Lötsch, Jörn, Johnston, Amy NB, Croy, Ilona, Hummel, T, Amy N. B. Johnston   +23 more
core   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Increased pain sensitivity in low blood pressure. [PDF]

, 2008
. There is broad evidence for a functional interaction between the cardiovascular and pain regulatory systems. One result of this interaction is the reduced sensitivity to acute pain in individuals with elevated blood pressure, which has been established
Duschek, Stefan, R. Sch, Schandry, Rainer, W. Schwarzkopf, S. Duschek, Schwarzkopf, W.   +5 more
core  

Pain Tolerance and Athletic Participation

, 1966
Using thermal, gross pressure, and muscle ischemia testing procedures to induce pain, an effort was made to determine the relationship between pain response and athletic participation by measuring the pain threshold and pain tolerance levels of three ...
Charles R. Kovacic, E. Dean Ryan
core   +1 more source

SERS Facemask for Rapid and Portable Sensing Mycobacterium Tuberculosis Antigens for TB Screening

Advanced Science, EarlyView.
Our study introduced an Au─Ag embedded covalent organic framework (U@COF) ‐mediated facemask for sensing TB antigen ESAT‐6/CFP‐10 complex in clinical droplet samples toward TB screening. Practical analysis of clinical samples demonstrated the availability of our facemask, which is capable of identifying the TB subjects (N = 17) from healthy candidates (
Lingzhi Chen, Jiaqi Yu, Jing Xu, Lingqi Chen, Ninghao Zhang, Wenrui Li, Runmin Zeng, Xiaomin Luo, Yiqun Chang, Jiayin Lai, Wenshi Huang, Xiaochen Liang, Ting Zhao, Shanze Chen, Huaihong Cai, Yanguang Cong, Pinghua Sun, Jiang Pi, Xueqin Huang, Haibo Zhou, Junxia Zheng   +20 more
wiley   +1 more source

The relationship between spiritual and emotional intelligence and pain tolerance in orthopedic surgery patients in Baghdad, Iraq [PDF]

Journal of Research Development in Nursing and Midwifery
Background: Postoperative orthopedic pain is challenging; inadequate control prolongs hospitalization and increases costs. The present study examined the relationship between spiritual intelligence and emotional intelligence and pain tolerance.
Arefe Fattah, Eman Al-Awabdeh, Alaa Jawad Kadhim, Masoome Ghotbi, Richard Mottershead, Hamid Reza Khosravizade Tabasi, Erfan Rajabi, Hadi Ahmadi Chenari   +7 more
doaj  

Physical Activity and Pain Perception in Residents Under Conditions of Chronic Hypoxia

Oxygen
(1) Background: Previous studies indicate that individuals who engage in regular physical activity have a higher pain threshold than those who do not exercise.
Margot Evelin Bernedo-Itusaca, Kely Melina Vilca-Coaquira, Ángel Gabriel Calisaya-Huacasi, Madeleyne Rosmery Cosi-Cupi, Stanley Rivaldo Leqque-Santi, Shantal Cutipa-Tinta, Alberto Salazar-Granara, Yony Martin-Pino Vanegas, Alcides Flores-Paredes, Shihui Guo, William Li, Moua Yang, Ginés Viscor, Ivan Hancco Zirena   +13 more
doaj   +1 more source

B Vitamins Potentiate Acute Morphine Antinociception and Attenuate the Development of Tolerance to Chronic Morphine in Mice

, 2017
Opiate analgesics are the most effective treatments for severe pain, but their clinical utility is often hampered by the development of analgesic tolerance. There are striking similarities between morphine actions and neuropathic pain.
Xue-Jun Song, Wen-Tao Liu, Han, Yuan, Xue-Ting Deng, Liu, Wen-Tao, Song, Xue-Jun, Yuan Han, Deng, Xue-Ting   +7 more
core   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source