Results 81 to 90 of about 176,534 (288)

Tolerable Pain [PDF]

Journal of Adolescent Health, 2022
openaire   +2 more sources

The influence of discouragement, anxiety and anger on pain: an examination of the role of endogenous opioids

, 2005
Animal research suggests that exposure to inescapable stressors can lead to an endogenous opioid-mediated form of pain inhibition, known as stress-induced analgesia (SIA).
Frew, Ashley Kim
core  

Interactive and Passive Mixed Reality Distraction: Effects on Cold Pressor Pain in Adults [PDF]

While interactive distractors are predicted to be more effective in reducing acute pain than passive distractors, the underlying mechanisms remain poorly understood.
Murray, Jamie, Caes, Line, Jamie G. Murray, Murray, Jamie G., Line Caes   +4 more
core   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source

Does It Hurt? Depends on Who's Asking

Psychological Topics, 2019
The aim of this paper is to determine whether experimenter's professional status (Study 1) and familiarity (Study 2) affect participant's pain assessment, even when there are no other differences in the experimenter's characteristics.
Koraljka Modić Stanke, Dragutin Ivanec, Luka Butić   +2 more
doaj   +2 more sources

Pain Perception Threshold in Young High-Altitude Natives After Acute Exposure to Severe Hypoxic Conditions

Oxygen
Previous studies indicate that individuals at high altitudes have a lower pain threshold than those living at sea level. This study evaluates the differences in pain perception among young people living at an altitude of 3800 m and after acute exposure ...
Kely Melina Vilca-Coaquira, Angel Gabriel Calisaya-Huacasi, Jeancarlo Tejada-Flores, Henry Oscar Tintaya-Ramos, Mariela Mercedes Quispe-Trujillo, Solanyela Anny Quispe-Humpiri, Rossela Alejandra Rojas-Chambilla, Gilberto Félix Peña-Vicuña, Alberto Salazar Granara, Luis F. Lens Sardón, Alcides Flores-Paredes, Moua Yang, Ginés Viscor, Ivan Hancco Zirena   +13 more
doaj   +1 more source

A Comparison of Maternal versus Paternal Nonverbal Behavior During Child Pain [PDF]

, 2016
Parental behavior plays a significant role in children's pain response. Prior research has found generally no differences between mothers’ and fathers’ verbal behavior during child pain.
Schinkel, Meghan G., Caes, Line, Moon, Erin C, Chambers, Christine T., Moon, Erin C., Chambers, Christine T, Schinkel, Meghan   +6 more
core   +1 more source

m6A‐Mediated Glycolysis by IL‐37 Drives T Cell Metabolic Reprogramming to Regulate Colitis

Advanced Science, EarlyView.
This study identifies an IL‐37/SIGIRR‐METTL14 regulatory axis that suppresses global m6A modification in CD4+ T cells. IL‐37 signaling, mediated through SIGIRR, inhibits IRAK4 and JNK phosphorylation, leading to downregulation of the methyltransferase METTL14.
Xiaoyan Wang, Jiadong Yu, Guolin Li, Ya Li, Fanlian Zeng, Jing Hu, Yifan Zhou, Chengcheng Yue, Qixiang Zhao, Chen Zhang, Hong Zhou, Fulei Zhao, Yawen Hu, Pei Zhou, Linna Gu, Yuting Feng, Mingxiang He, Shishi Huang, Xiaochi Sun, Xinmeng Wang, Jie Tang, Xinyu Zeng, Wenling Wu, Nongyu Huang, Xinai Cui, Kaijun Cui, Jiong Li   +26 more
wiley   +1 more source

Exposure and the reduction of fear of pain [PDF]

, 2012
This research investigated interoceptive exposure as a treatment option for disabling pain-related fear. Interoceptive exposure was conceptualised as an extension of the Fear Avoidance Model and a literature review highlighted three important areas ...
Taylor, Siobhan Catherine
core