Results 31 to 40 of about 1,392,716 (205)

Long-lasting pain-related behaviors in mouse chronic cystitis model induced by a single intravesical injection of hydrogen peroxide

Journal of Pharmacological Sciences, 2015
We previously established a long-lasting cystitis model by an intravesical injection of hydrogen peroxide (H2O2) into mice. In this study, we assessed the pain-related behaviors in the cystitis model.
Koji Dogishi, Mizuki Kodera, Shohei Oyama, Hisashi Shirakawa, Takayuki Nakagawa, Shuji Kaneko   +5 more
doaj   +1 more source

A mouse model for interstitial cystitis/painful bladder syndrome based on APF inhibition of bladder epithelial repair: a pilot study

BMC Urology, 2012
Background Interstitial cystitis/painful bladder syndrome (IC/PBS) is a chronic bladder disorder with bladder epithelial thinning or ulceration, pain, urinary frequency and urgency.
Keay Susan, Leitzell Samantha, Ochrzcin Ashley, Clements George, Zhan Min, Johnson David   +5 more
doaj   +1 more source

Evaluation of Patients with Painful Bladder Syndrome/Interstitial Cystitis

The Scientific World Journal, 2005
This review looks into the evaluation of patients with interstitial cystitis (IC). Interstitial cystitis is not easy to define. There is a lot of activity in this domain and a great international effort is made to get to a generally accepted definition ...
Jean Jacques Wyndaele
doaj   +1 more source

Urinary proteomics evaluation in interstitial cystitis/painful bladder syndrome: a pilot study

International Brazilian Journal of Urology, 2010
PURPOSE: Interstitial cystitis/painful bladder syndrome (IC/PBS) is characterized by chronic pain, pressure and discomfort felt in the pelvis or bladder.
Young Ah Goo, Yihsuan S. Tsai, Alvin Y. Liu, David R. Goodlett, Claire C. Yang   +4 more
doaj   +1 more source

Can Botulinum Toxin A Play a Role in Treatment of Chronic Pelvic Pain Syndrome in Female Patients?—Clinical and Animal Evidence

Toxins, 2020
Chronic pelvic pain (CPP) is defined as chronic pain and inflammation in the pelvic organs for more than six months. There are wide ranges of clinical presentations, including pelvic pain, painful intercourse, irritable bowel syndrome, and pain during ...
Chin-Li Chen, En Meng
doaj   +1 more source

PAINFUL BLADDER SYNDROME: DIAGNOSIS AND PATHOPHSIOLOGY

Urology Research and Practice, 2019
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Cüneyt ÖZKÜRKÇÜGİL
doaj   +2 more sources

Interstitial Cystitis/Painful Bladder Syndrome and Associated Medical Conditions With an Emphasis on Irritable Bowel Syndrome, Fibromyalgia and Chronic Fatigue Syndrome

, 2010
Purpose: We characterized and compared the impact of clinical phenotypic associations between interstitial cystitis/painful bladder syndrome and controls in relation to potentially related conditions, particularly irritable bowel syndrome, fibromyalgia ...
Yang, Cheng, Dean A. Tripp, Pontari, M., J. Curtis Nickel, Jorgen Nordling, Claire C. Yang, Nickel, J.C., Ragi Doggweiler, Mayer, R., Doggweiler, R., Tripp, D.A., Michel Pontari, Nagendra Mishra, Robert Mayer, Robert Moldwin, Moldwin, R., Carr, L.K., Nordling, J., Lesley K. Carr, Mishra, N.   +19 more
core   +1 more source

The Expression of Inflammatory Mediators in Bladder Pain Syndrome [PDF]

European Urology, 2016
Bladder pain syndrome (BPS) pathology is poorly understood. Treatment strategies are empirical, with limited efficacy, and affected patients have diminished quality of life.We examined the hypothesis that inflammatory mediators within the bladder contribute to BPS pathology.Fifteen women with BPS and 15 women with stress urinary incontinence without ...
Offiah, Ifeoma, Didangelos, Athanasios, Dawes, John, Cartwright, Rufus, Khullar, Vik, Bradbury, Elizabeth J., O'Sullivan, Suzanne, Williams, Dic, Chessell, Iain P., Pallas, Kenny, Graham, Gerry, O’Reilly, Barry A., McMahon, Stephen B.   +12 more
openaire   +6 more sources

Morphology‐Dependent Bioadhesion and Bioelimination of Hyaluronan Particles Administered in the Bladder

Advanced NanoBiomed Research, 2022
Intravesical instillation allows for direct exposure of the urothelium to a drug. However, the therapeutic efficacy is often limited by the rapid elimination of the drug from the bladder.
Raul Diaz-Salmeron, Balthazar Toussaint, Catherine Cailleau, Gilles Ponchel, Kawthar Bouchemal   +4 more
doaj   +1 more source

Reflex seizures and epilepsy surgery: A network approach case‐based exploration

Epileptic Disorders, EarlyView.
Abstract Context Reflex seizures (RS) are defined by their consistent provocation by specific stimuli, encompassing a broad range from elementary sensory inputs to complex cognitive tasks. While RS are often encountered in clinical practice, their surgical management remains sparsely reported and poorly systematized.
Olivier Aron, Laure Salmon, Nicolas Nguyen, Dènahin Toffa, Sami Obaid, Alexis Robin, Dang Khoa Nguyen   +6 more
wiley   +1 more source